STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
cpsYTranscriptional regulator, LysR family, putative; GC: 44.55%; Codon Adaptation Index (CAI): 0.758. Helix-turn-helix prediction: LysR. Possible capsular polysaccharide biosynthesis regulator. Curator(s): J. Alves; Protein involved in regulation of transcription, DNA-dependent; Belongs to the LysR transcriptional regulatory family. (302 aa)    
Predicted Functional Partners:
glgD
Glycogen biosynthesis protein GlgD, putative; GC: 42.89%; Codon Adaptation Index (CAI): 0.775. Curator(s): X. Ge; Protein involved in nucleotidyltransferase activity.
     
 0.655
pyrD
Dihydroorotate dehydrogenase B, putative; Catalyzes the conversion of dihydroorotate to orotate.
   
 
 0.625
pyrK
Dihydroorotate dehydrogenase electron transfer subunit, putative; Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD(+).
     
 0.611
SSA_2222
Tyrosine-protein kinase Wze, putative; GC: 45.06%; Transporter classification TC:8.A.3.2.2. Codon Adaptation Index (CAI): 0.757. Curator(s): J. Alves; Protein involved in capsule polysaccharide biosynthesis.
     
 0.571
SSA_2223
Capsular polysaccharide biosynthesis protein Wzd (chain length regulator), putative; GC: 46.12%; Transporter classification TC:8.A.3.2.1. Transmembrane domains: 2. Codon Adaptation Index (CAI): 0.787. Curator(s): J. Alves.
     
 0.571
SSA_2224
Phosphotyrosine-protein phosphatase, putative; GC: 44.81%; Codon Adaptation Index (CAI): 0.774; Protein involved in hydrolase activity.
     
 0.571
metF
5,10-methylenetetrahydrofolate reductase, putative; GC: 45.39%; Codon Adaptation Index (CAI): 0.772. Curator(s): M. Chaplin; Protein involved in oxidoreductase activity; Belongs to the methylenetetrahydrofolate reductase family.
 
  
 0.560
SSA_1244
Hypothetical protein; GC: 38.33%; Transmembrane domains: 1. Codon Adaptation Index (CAI): 0.742. SignalP prediction: Yes (prob. 0.456).
       0.555
SSA_0917
Cobalamin-independent methionine synthase II, putative; GC: 48.28%; Codon Adaptation Index (CAI): 0.765. Curator(s): T. Kitten, J. Alves; Protein involved in methionine biosynthesis.
 
  
 0.550
rpoA
DNA-directed RNA polymerase, alpha chain, putative; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
   
 
 0.538
Your Current Organism:
Streptococcus sanguinis SK36
NCBI taxonomy Id: 388919
Other names: S. sanguinis SK36, Streptococcus sanguinis str. SK36, Streptococcus sanguinis strain SK36
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