STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
SSA_1600Hypothetical protein; GC: 40.4%; Transmembrane domains: 1. Codon Adaptation Index (CAI): 0.732. Curator(s): J. Alves. (32 aa)    
Predicted Functional Partners:
smpB
VacB-like protein, putative; Required for rescue of stalled ribosomes mediated by trans- translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then swit [...]
       0.773
vacB
Exoribonuclease, VacB/Rnb family, putative; 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs.
       0.773
SSA_1603
Conserved hypothetical protein; GC: 33.01%; Codon Adaptation Index (CAI): 0.744.
       0.645
SSA_1599
Hypothetical protein; GC: 32.62%; Transmembrane domains: 1. Codon Adaptation Index (CAI): 0.757. LipoP prediction: SpI. SignalP prediction: Yes (prob. 0.999); Curator(s): J. Alves.
       0.556
secG
Protein-export membrane protein secG, putative; Involved in protein export. Participates in an early event of protein translocation; Belongs to the SecG family.
       0.400
Your Current Organism:
Streptococcus sanguinis SK36
NCBI taxonomy Id: 388919
Other names: S. sanguinis SK36, Streptococcus sanguinis str. SK36, Streptococcus sanguinis strain SK36
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