STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
SSA_1683NrdI protein, putative; GC: 45.7%; Codon Adaptation Index (CAI): 0.785; Protein involved in molecular function unknown; Belongs to the NrdI family. (123 aa)    
Predicted Functional Partners:
nrdF
Ribonucleoside-diphosphate reductase 2, beta subunit, putative; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides; Belongs to the ribonucleoside diphosphate reductase small chain family.
  
 
 0.921
SSA_1684
Histidine kinase, putative; GC: 44.04%; Transmembrane domains: 2. Codon Adaptation Index (CAI): 0.792. SignalP prediction: Yes (prob. 0.717); Protein involved in transferase activity, transferring phosphorus-containing groups.
       0.718
SSA_1685
Two-component response transcriptional regulator; GC: 45.71%; Codon Adaptation Index (CAI): 0.762. Curator(s): J. Alves; Protein involved in sensory perception and regulation of transcription, DNA-dependent.
       0.718
nrdE
Ribonucleoside-diphosphate reductase, putative; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.
  
  
 0.661
nrdH
Glutaredoxin-like protein, putative; GC: 39.27%; Codon Adaptation Index (CAI): 0.804. Involved in electron transport system for ribonucleotide reductase system NrdEF. Curator(s): X. Ge; Protein involved in cell redox homeostasis.
  
  
 0.638
SSA_1686
Conserved hypothetical protein; GC: 46.67%; Codon Adaptation Index (CAI): 0.774; Protein involved in hydrolase activity.
       0.490
SSA_1682
Conserved hypothetical protein; GC: 45.77%; Transmembrane domains: 8. Codon Adaptation Index (CAI): 0.733.
       0.478
SSA_2198
Conserved hypothetical protein; GC: 47.31%; Codon Adaptation Index (CAI): 0.79.
  
     0.456
Your Current Organism:
Streptococcus sanguinis SK36
NCBI taxonomy Id: 388919
Other names: S. sanguinis SK36, Streptococcus sanguinis str. SK36, Streptococcus sanguinis strain SK36
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