Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
SSA_1685Two-component response transcriptional regulator; GC: 45.71%; Codon Adaptation Index (CAI): 0.762. Curator(s): J. Alves; Protein involved in sensory perception and regulation of transcription, DNA-dependent. (228 aa)    
Predicted Functional Partners:
SSA_1684
Histidine kinase, putative; GC: 44.04%; Transmembrane domains: 2. Codon Adaptation Index (CAI): 0.792. SignalP prediction: Yes (prob. 0.717); Protein involved in transferase activity, transferring phosphorus-containing groups.
 0.999
SSA_1680
ABC-type bacitracin resistance protein A, permease component, putative; GC: 43.68%; Transporter classification TC:3.A.1.123.4. Transmembrane domains: 10. Codon Adaptation Index (CAI): 0.774. LipoP prediction: SpI. SignalP prediction: Yes (prob. 0.981); Curator(s): J. Alves.
 
   
 0.940
SSA_1659
ABC-type antimicrobial peptide transport system, permease component, putative; GC: 36.85%; Transporter classification TC:3.A.1.123.4. Transmembrane domains: 11. Codon Adaptation Index (CAI): 0.757. SignalP prediction: Yes (prob. 0.98); Curator(s): J. Alves.
 
   
 0.846
SSA_1564
Histidine kinase, putative; GC: 44.96%; Transporter classification TC:2.A.21.9.1. Transmembrane domains: 1. Codon Adaptation Index (CAI): 0.774; Protein involved in transferase activity, transferring phosphorus-containing groups.
 
 
 0.843
SSA_1681
ABC-type bacitracin resistance protein A, ATPase component, putative; GC: 48.46%; Transporter classification TC:3.A.1.123.4. Codon Adaptation Index (CAI): 0.754. Curator(s): J. Alves; Protein involved in nucleoside-triphosphatase activity.
 
   
 0.824
SSA_1114
Histidine kinase, putative; GC: 40.77%; Transporter classification TC:2.A.21.9.2. Transmembrane domains: 2. Codon Adaptation Index (CAI): 0.747. SignalP prediction: Yes (prob. 0.727); Protein involved in transferase activity, transferring phosphorus-containing groups.
 
 
 0.808
SSA_0402
Histidine kinase, putative; GC: 48.4%; Transmembrane domains: 1. Codon Adaptation Index (CAI): 0.769. SignalP prediction: Yes (prob. 0.46); Helix-turn-helix prediction: AraC. Curator(s): T. Kitten; Protein involved in transferase activity, transferring phosphorus-containing groups and kinase activity.
 
 
 0.801
nisK
NisK (sensor-receptor histidine kinase domain), putative; GC: 42.58%; Transporter classification TC:2.A.21.9.2. Transmembrane domains: 2. Codon Adaptation Index (CAI): 0.784. Curator(s): P. Manque, J. Alves; Protein involved in transferase activity, kinase activity and transferase activity, transferring phosphorus-containing groups.
 
 
 0.797
SSA_1660
ABC-type antimicrobial peptide transport system, ATPase component, putative; GC: 48.95%; Transporter classification TC:3.A.1.123.4. Codon Adaptation Index (CAI): 0.752. Curator(s): J. Alves; Protein involved in nucleoside-triphosphatase activity.
 
   
 0.760
SSA_0897
Two component system histidine kinase, putative; GC: 45.27%; Transporter classification TC:2.A.21.9.2. Transmembrane domains: 2. Codon Adaptation Index (CAI): 0.78. LipoP prediction: SpI. SignalP prediction: Yes (prob. 0.982); Curator(s): L. Ozaki; Protein involved in transferase activity, transferring phosphorus-containing groups.
 
 
 0.751
Your Current Organism:
Streptococcus sanguinis SK36
NCBI taxonomy Id: 388919
Other names: S. sanguinis SK36, Streptococcus sanguinis str. SK36, Streptococcus sanguinis strain SK36
Server load: medium (46%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.