STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
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Co-occurrence
Co-expression
Experiments
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[Homology]
Score
SSA_1773Conserved hypothetical protein; Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins; Belongs to the prokaryotic riboflavin transporter (P-RFT) (TC 2.A.87) family. (185 aa)    
Predicted Functional Partners:
SSA_1772
Conserved hypothetical protein; GC: 45.16%; Transmembrane domains: 6. Codon Adaptation Index (CAI): 0.748.
       0.787
SSA_1771
Conserved DNA methyltransferase protein, putative; GC: 51.13%; Codon Adaptation Index (CAI): 0.766; Protein involved in transferase activity and DNA repair.
       0.693
SSA_1769
Conserved hypothetical protein; GC: 50%; Codon Adaptation Index (CAI): 0.766; Protein involved in transferase activity.
  
    0.667
SSA_1770
Conserved hypothetical protein; GC: 49.16%; Codon Adaptation Index (CAI): 0.768; Protein involved in iron ion binding.
       0.667
stpA
ABC-type cobalt transport system, ATPase component, putative; ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates.
 
   
 0.656
ecfA2
ABC-type cobalt transport system, ATPase component, putative; ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates.
 
   
 0.620
cspR
RRNA methylase, putative; Could methylate the ribose at the nucleotide 34 wobble position in tRNA; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily.
       0.592
ecfT
Cobalt transport protein cbiQ, putative; Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates.
 
   
 0.549
SSA_2000
Conserved hypothetical protein; GC: 44.72%; Transmembrane domains: 5. Codon Adaptation Index (CAI): 0.758. SignalP prediction: Yes (prob. 0.865).
  
   
 0.547
ccl
Citrulline cluster-linked gene, putative; GC: 37.98%; Transmembrane domains: 5. Codon Adaptation Index (CAI): 0.808.
  
     0.539
Your Current Organism:
Streptococcus sanguinis SK36
NCBI taxonomy Id: 388919
Other names: S. sanguinis SK36, Streptococcus sanguinis str. SK36, Streptococcus sanguinis strain SK36
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