STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
SSA_1817Conserved uncharacterized protein; GC: 33.48%; Codon Adaptation Index (CAI): 0.75. Curator(s): J. Alves; Protein involved in endonuclease activity. (905 aa)    
Predicted Functional Partners:
SSA_1816
Conserved hypothetical protein; GC: 34.25%; Codon Adaptation Index (CAI): 0.751.
 
     0.951
guaB
Inosine-5'-monophosphate dehydrogenase, putative; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
   
 0.913
SSA_1812
Modification methylase, putative; GC: 29.83%; Codon Adaptation Index (CAI): 0.737; Protein involved in transferase activity.
 
  
 0.896
SSA_0736
Catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases, putative; GC: 42.07%; Codon Adaptation Index (CAI): 0.805. Curator(s): X. Ge; Protein involved in regulation of transcription, DNA-dependent.
    
 0.837
SSA_1818
Very short patch repair endonuclease, putative; May nick specific sequences that contain T:G mispairs resulting from m5C-deamination.
 
     0.831
SSA_1813
Hypothetical protein; GC: 30.65%; Codon Adaptation Index (CAI): 0.735.
       0.792
SSA_1814
Conserved hypothetical protein; GC: 32.6%; Codon Adaptation Index (CAI): 0.756.
       0.792
SSA_1815
Conserved hypothetical protein; GC: 32.15%; Codon Adaptation Index (CAI): 0.765.
       0.792
dnaJ
Chaperone protein dnaJ, putative; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions betwe [...]
   
 0.784
crpB
CshA-like fibrillar surface protein B; GC: 46.38%; Codon Adaptation Index (CAI): 0.797. LipoP prediction: SpI. SignalP prediction: Yes (prob. 1); Curator(s): T. Kitten, J. Alves; Protein involved in pathogenesis.
  
     0.719
Your Current Organism:
Streptococcus sanguinis SK36
NCBI taxonomy Id: 388919
Other names: S. sanguinis SK36, Streptococcus sanguinis str. SK36, Streptococcus sanguinis strain SK36
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