STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
nusAN utilization substance protein A, putative; Participates in both transcription termination and antitermination. (420 aa)    
Predicted Functional Partners:
SSA_1897
Ribosomal protein HS6-type (S12/L30/L7a), putative; GC: 44.78%; Codon Adaptation Index (CAI): 0.804. Curator(s): J. Alves; Protein involved in structural constituent of ribosome.
  
  
 0.990
SSA_1899
Conserved hypothetical protein; GC: 44.44%; Codon Adaptation Index (CAI): 0.768.
  
    0.989
infB
Translation initiation factor IF-2, putative; One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
  
 0.988
rimP
Conserved uncharacterized protein; Required for maturation of 30S ribosomal subunits. Belongs to the RimP family.
  
  
 0.984
rpoB
DNA-directed RNA polymerase I, beta chain (140 kDa subunit), putative; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
 
 
 0.979
rpoA
DNA-directed RNA polymerase, alpha chain, putative; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
 
 
 0.973
nusG
Transcription antitermination factor NusG, putative; Participates in transcription elongation, termination and antitermination.
 
 
 0.958
rpoC
DNA-directed RNA polymerase I, beta chain (160 kDa subunit), putative; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
 
   0.957
rpsG
30S ribosomal protein S7, putative; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA; Belongs to the universal ribosomal protein uS7 family.
  
 
 0.942
rplA
50S ribosomal protein L1, putative; Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
  
 
 0.941
Your Current Organism:
Streptococcus sanguinis SK36
NCBI taxonomy Id: 388919
Other names: S. sanguinis SK36, Streptococcus sanguinis str. SK36, Streptococcus sanguinis strain SK36
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.