Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
hitDiadenosine tetraphosphate (Ap4A) hydrolase; GC: 44.77%; Codon Adaptation Index (CAI): 0.802. Curator(s): J. Alves. (136 aa)    
Predicted Functional Partners:
SSA_1907
Conserved hypothetical protein; GC: 37.15%; Codon Adaptation Index (CAI): 0.755.
       0.849
SSA_1904
ABC-type multidrug transport system, permease component, putative; GC: 44.32%; Transmembrane domains: 8. Codon Adaptation Index (CAI): 0.767. Curator(s): J. Alves.
     
 0.816
cobB
NAD-dependent deacetylase, putative; NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form; Belongs to the sirtuin family. Class U subfamily.
  
 
  0.770
glnA
Glutamine synthetase type 1, putative; GC: 45.06%; Codon Adaptation Index (CAI): 0.803. Curator(s): T. Kitten; Protein involved in ligase activity; Belongs to the glutamine synthetase family.
  
   0.741
SSA_1903
Conserved hypothetical protein; GC: 47.55%; Codon Adaptation Index (CAI): 0.759.
     
 0.701
trmB
tRNA (guanine-N(7)-)-methyltransferase, putative; Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
       0.690
SSA_1905
ABC-type multidrug transport system, ATPase component, putative; GC: 44.99%; Transporter classification TC:3.A.1.126.1. Codon Adaptation Index (CAI): 0.774. Curator(s): J. Alves; Protein involved in nucleoside-triphosphatase activity.
  
  
 0.672
rimP
Conserved uncharacterized protein; Required for maturation of 30S ribosomal subunits. Belongs to the RimP family.
       0.538
SSA_1897
Ribosomal protein HS6-type (S12/L30/L7a), putative; GC: 44.78%; Codon Adaptation Index (CAI): 0.804. Curator(s): J. Alves; Protein involved in structural constituent of ribosome.
  
    0.525
nusA
N utilization substance protein A, putative; Participates in both transcription termination and antitermination.
       0.521
Your Current Organism:
Streptococcus sanguinis SK36
NCBI taxonomy Id: 388919
Other names: S. sanguinis SK36, Streptococcus sanguinis str. SK36, Streptococcus sanguinis strain SK36
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