STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
SSA_1995Conserved hypothetical protein; GC: 43.81%; Codon Adaptation Index (CAI): 0.779. (228 aa)    
Predicted Functional Partners:
rpoE
DNA-directed RNA polymerase delta subunit, putative; Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling; Belongs to the RpoE family.
       0.532
pyrG
CTP synthase, putative; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
       0.452
SSA_0699
Methyltransferase, putative; GC: 31.73%; Codon Adaptation Index (CAI): 0.758. Curator(s): P. Xu; Protein involved in transferase activity.
  
     0.442
SSA_1591
Dipeptidase, putative; GC: 46.12%; Transmembrane domains: 1. Codon Adaptation Index (CAI): 0.776. LipoP prediction: SpI. SignalP prediction: Yes (prob. 0.927); Protein involved in dipeptidase activity and hydrolase activity.
  
     0.428
SSA_1593
Dipeptidase, putative; GC: 44.38%; Transmembrane domains: 2. Codon Adaptation Index (CAI): 0.782. LipoP prediction: SpI. SignalP prediction: Yes (prob. 0.998); Protein involved in dipeptidase activity and hydrolase activity.
  
     0.426
Your Current Organism:
Streptococcus sanguinis SK36
NCBI taxonomy Id: 388919
Other names: S. sanguinis SK36, Streptococcus sanguinis str. SK36, Streptococcus sanguinis strain SK36
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