STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
SSA_1999Conserved hypothetical protein; GC: 48.4%; Codon Adaptation Index (CAI): 0.774; Protein involved in molecular function unknown; Belongs to the UPF0340 family. (187 aa)    
Predicted Functional Partners:
SSA_2000
Conserved hypothetical protein; GC: 44.72%; Transmembrane domains: 5. Codon Adaptation Index (CAI): 0.758. SignalP prediction: Yes (prob. 0.865).
 
    0.948
lacB
Galactose-6-phosphate isomerase, LacB subunit, putative; GC: 39.15%; Codon Adaptation Index (CAI): 0.818; Protein involved in intramolecular oxidoreductase activity, interconverting aldoses and ketoses and galactose-6-phosphate isomerase activity.
 
    0.874
thiD
Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase, putative; GC: 46.04%; Codon Adaptation Index (CAI): 0.765; Protein involved in phosphomethylpyrimidine kinase activity and kinase activity.
       0.846
truA
tRNA pseudouridine synthase A, putative; Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
       0.846
ropA
Trigger factor, putative; Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase; Belongs to the FKBP-type PPIase family. Tig subfamily.
       0.743
hemK
HemK protein, putative; Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif; Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily.
      0.735
lacA
Conserved hypothetical protein; GC: 45.83%; Codon Adaptation Index (CAI): 0.805.
  
    0.646
dnaJ
Chaperone protein dnaJ, putative; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions betwe [...]
       0.521
zmpB
Zinc metalloprotease zmpB precursor, putative; GC: 46.16%; Transmembrane domains: 3. Codon Adaptation Index (CAI): 0.781. LipoP prediction: SpI. SignalP prediction: Yes (prob. 1); Protein involved in metal ion binding.
       0.429
fur
Fe2+/Zn2+ uptake regulation protein, putative; GC: 47.07%; Codon Adaptation Index (CAI): 0.786. Curator(s): P. Xu; Protein involved in regulation of transcription, DNA-dependent; Belongs to the Fur family.
       0.401
Your Current Organism:
Streptococcus sanguinis SK36
NCBI taxonomy Id: 388919
Other names: S. sanguinis SK36, Streptococcus sanguinis str. SK36, Streptococcus sanguinis strain SK36
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