STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
truAtRNA pseudouridine synthase A, putative; Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs. (249 aa)    
Predicted Functional Partners:
thiD
Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase, putative; GC: 46.04%; Codon Adaptation Index (CAI): 0.765; Protein involved in phosphomethylpyrimidine kinase activity and kinase activity.
  
    0.929
SSA_2000
Conserved hypothetical protein; GC: 44.72%; Transmembrane domains: 5. Codon Adaptation Index (CAI): 0.758. SignalP prediction: Yes (prob. 0.865).
       0.855
SSA_1999
Conserved hypothetical protein; GC: 48.4%; Codon Adaptation Index (CAI): 0.774; Protein involved in molecular function unknown; Belongs to the UPF0340 family.
       0.846
ecfT
Cobalt transport protein cbiQ, putative; Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates.
  
  
 0.821
truB
tRNA pseudouridine synthase B, putative; Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs; Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
  
 
 0.812
rpoA
DNA-directed RNA polymerase, alpha chain, putative; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
  
  
 0.810
mraW
S-adenosyl-methyltransferase mraW, putative; Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.
  
 
 0.778
ropA
Trigger factor, putative; Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase; Belongs to the FKBP-type PPIase family. Tig subfamily.
  
  
 0.731
ecfA2
ABC-type cobalt transport system, ATPase component, putative; ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates.
  
  
 0.695
rpsI
30S ribosomal protein S9, putative; GC: 45.8%; Codon Adaptation Index (CAI): 0.784; Belongs to the universal ribosomal protein uS9 family.
  
 
 0.687
Your Current Organism:
Streptococcus sanguinis SK36
NCBI taxonomy Id: 388919
Other names: S. sanguinis SK36, Streptococcus sanguinis str. SK36, Streptococcus sanguinis strain SK36
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