close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
zmpBZinc metalloprotease zmpB precursor, putative; GC: 46.16%; Transmembrane domains: 3. Codon Adaptation Index (CAI): 0.781. LipoP prediction: SpI. SignalP prediction: Yes (prob. 1); Protein involved in metal ion binding. (1904 aa)    
Predicted Functional Partners:
SSA_1816
Conserved hypothetical protein; GC: 34.25%; Codon Adaptation Index (CAI): 0.751.
  
     0.766
SSA_1594
Metalloendopeptidase, putative; GC: 41.79%; Transmembrane domains: 1. Codon Adaptation Index (CAI): 0.79. LipoP prediction: SpI. SignalP prediction: Yes (prob. 0.816); Protein involved in metal ion binding and hydrolase activity.
      
 0.730
SSA_1181
Hydrolase, alpha/beta superfamily, putative; GC: 43.39%; Codon Adaptation Index (CAI): 0.797; Protein involved in catalytic activity.
  
     0.650
SSA_1812
Modification methylase, putative; GC: 29.83%; Codon Adaptation Index (CAI): 0.737; Protein involved in transferase activity.
  
     0.609
SSA_1179
Carbamoylphosphate synthase large subunit / biotin carboxylase, putative; GC: 43.27%; Codon Adaptation Index (CAI): 0.796. Curator(s): J. Alves; Protein involved in ligase activity.
  
     0.582
crpA
CshA-like fibrillar surface protein A; GC: 46.68%; Transmembrane domains: 1. Codon Adaptation Index (CAI): 0.801. LipoP prediction: SpI. SignalP prediction: Yes (prob. 1); Curator(s): L. Ozaki, J. Alves; Protein involved in calcium ion binding and pathogenesis.
 
   
 0.558
crpB
CshA-like fibrillar surface protein B; GC: 46.38%; Codon Adaptation Index (CAI): 0.797. LipoP prediction: SpI. SignalP prediction: Yes (prob. 1); Curator(s): T. Kitten, J. Alves; Protein involved in pathogenesis.
 
   
 0.557
crpC
CshA-like fibrillar surface protein C; GC: 46.28%; Codon Adaptation Index (CAI): 0.794. LipoP prediction: SpI. SignalP prediction: Yes (prob. 1); Curator(s): T. Kitten, J. Alves; Protein involved in pathogenesis.
 
   
 0.554
SSA_1180
Conserved hypothetical protein; GC: 45.75%; Codon Adaptation Index (CAI): 0.802.
  
     0.546
SSA_2149
Conserved hypothetical protein; GC: 36.94%; Transmembrane domains: 2. Codon Adaptation Index (CAI): 0.757. SignalP prediction: Yes (prob. 0.721).
  
     0.532
Your Current Organism:
Streptococcus sanguinis SK36
NCBI taxonomy Id: 388919
Other names: S. sanguinis SK36, Streptococcus sanguinis str. SK36, Streptococcus sanguinis strain SK36
Server load: low (22%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.