STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
SSA_2018Conserved hypothetical protein; GC: 49.93%; Codon Adaptation Index (CAI): 0.763; Protein involved in molecular function unknown. (445 aa)    
Predicted Functional Partners:
SSA_2019
Conserved hypothetical protein; GC: 40.45%; Codon Adaptation Index (CAI): 0.783; Protein involved in amino acid binding.
 
     0.965
hrcA
Heat shock transcription repressor HrcA, putative; Negative regulator of class I heat shock genes (grpE-dnaK- dnaJ and groELS operons). Prevents heat-shock induction of these operons.
       0.516
grpE
Molecular chaperone GrpE (HSP-70 cofactor), putative; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction [...]
       0.512
SSA_2017
Hypothetical protein (possibly membrane-associated); GC: 43.14%; Transmembrane domains: 4. Codon Adaptation Index (CAI): 0.756. Curator(s): J. Alves.
       0.492
SSA_2020
Conserved hypothetical protein; GC: 49.45%; Transmembrane domains: 1. Codon Adaptation Index (CAI): 0.78. LipoP prediction: SpI. SignalP prediction: Yes (prob. 1); Protein involved in proteolysis.
       0.456
polA
DNA polymerase I - 3'-5' exonuclease and polymerase domains, putative; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.
       0.436
SSA_2016
Phosphoglycerate mutase, putative; GC: 50.28%; Codon Adaptation Index (CAI): 0.781. Curator(s): J. Alves; Protein involved in phosphoglycerate mutase activity.
       0.430
gatB
Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B, putative; Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl- tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp- tRNA(Asn) or phospho-Glu-tRNA(Gln); Belongs to the GatB/GatE family. GatB subfamily.
  
    0.403
Your Current Organism:
Streptococcus sanguinis SK36
NCBI taxonomy Id: 388919
Other names: S. sanguinis SK36, Streptococcus sanguinis str. SK36, Streptococcus sanguinis strain SK36
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