Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Experiments
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[Homology]
Score
SSA_2022Transcriptional regulator, MerR family (multidrug-efflux transporter genes), putative; GC: 40.14%; Codon Adaptation Index (CAI): 0.782. Curator(s): J. Alves; Protein involved in regulation of transcription, DNA-dependent. (278 aa)    
Predicted Functional Partners:
SSA_2021
Conserved hypothetical protein; GC: 44.93%; Codon Adaptation Index (CAI): 0.806; Protein involved in lysine biosynthesis via diaminopimelate.
 
     0.781
rpoB
DNA-directed RNA polymerase I, beta chain (140 kDa subunit), putative; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
 
 0.512
glnA
Glutamine synthetase type 1, putative; GC: 45.06%; Codon Adaptation Index (CAI): 0.803. Curator(s): T. Kitten; Protein involved in ligase activity; Belongs to the glutamine synthetase family.
  
 
 0.485
rpoD
DNA-directed RNA polymerase, sigma subunit (sigma70/sigma32), putative; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.
  
 
 0.469
ctpA
Copper-translocating P-type ATPase, putative; GC: 47.93%; Transporter classification TC:3.A.3.5.1. Transmembrane domains: 8. Codon Adaptation Index (CAI): 0.753. LipoP prediction: SpI. Helix-turn-helix prediction: AraC. Curator(s): M. Serrano; Protein involved in metal ion transporter activity.
  
  
 0.464
rpoC
DNA-directed RNA polymerase I, beta chain (160 kDa subunit), putative; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
 
 0.412
rpoA
DNA-directed RNA polymerase, alpha chain, putative; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
   
   0.404
rpoZ
DNA-directed RNA polymerase, subunit K/omega, putative; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
   
   0.404
Your Current Organism:
Streptococcus sanguinis SK36
NCBI taxonomy Id: 388919
Other names: S. sanguinis SK36, Streptococcus sanguinis str. SK36, Streptococcus sanguinis strain SK36
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