Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
SSA_2052Thioredoxin, putative; GC: 47.62%; Codon Adaptation Index (CAI): 0.792; Protein involved in electron transport; Belongs to the thioredoxin family. (104 aa)    
Predicted Functional Partners:
SSA_1865
Thioredoxin reductase, putative; GC: 48.63%; Codon Adaptation Index (CAI): 0.781; Protein involved in removal of superoxide radicals.
 
 
 0.834
nrdE
Ribonucleoside-diphosphate reductase, putative; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.
  
 
 0.754
SSA_2053
Conserved hypothetical protein; GC: 40.09%; Codon Adaptation Index (CAI): 0.86.
  
    0.750
groEL
60 kDa chaperonin; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions.
   
 
 0.626
SSA_2054
Hypothetical protein; GC: 36.11%; Codon Adaptation Index (CAI): 0.803.
       0.598
SSA_0813
Thioredoxin reductase, putative; GC: 47.57%; Codon Adaptation Index (CAI): 0.781. Curator(s): X. Ge; Protein involved in oxidoreductase activity.
  
 
 0.576
acoL
Dihydrolipoamide dehydrogenase, putative; GC: 45.81%; Codon Adaptation Index (CAI): 0.808; Protein involved in FAD binding.
  
 
 0.570
SSA_2055
Conserved hypothetical protein; GC: 44.89%; Codon Adaptation Index (CAI): 0.816.
       0.514
tpx
Thiol peroxidase, putative; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides; Belongs to the peroxiredoxin family. Tpx subfamily.
  
 
 0.486
SSA_0065
Low molecular weight phosphotyrosine protein phosphatase, putative; GC: 44.68%; Codon Adaptation Index (CAI): 0.79. Curator(s): J. Alves; Protein involved in protein amino acid dephosphorylation; Belongs to the low molecular weight phosphotyrosine protein phosphatase family.
  
 
 0.443
Your Current Organism:
Streptococcus sanguinis SK36
NCBI taxonomy Id: 388919
Other names: S. sanguinis SK36, Streptococcus sanguinis str. SK36, Streptococcus sanguinis strain SK36
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