STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
cdsAPhosphatidate cytidylyltransferase, putative; GC: 46.77%; Transmembrane domains: 7. Codon Adaptation Index (CAI): 0.785. SignalP prediction: Yes (prob. 0.672); Protein involved in nucleotidyltransferase activity; Belongs to the CDS family. (267 aa)    
Predicted Functional Partners:
uppS
Undecaprenyl pyrophosphate synthetase, putative; Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.
  
  
 0.991
pgsA
CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase, putative; GC: 37.41%; Transmembrane domains: 3. Codon Adaptation Index (CAI): 0.785. SignalP prediction: Yes (prob. 0.554); Protein involved in transferase activity; Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
 
 
 0.961
plsC
1-acyl-sn-glycerol-3-phosphate acyltransferase, putative; GC: 42.91%; Transmembrane domains: 1. Codon Adaptation Index (CAI): 0.828. SignalP prediction: Yes (prob. 0.5); Curator(s): P. Xu, J. Alves; Protein involved in acyltransferase activity and transferase activity.
    
 0.938
SSA_1013
Phosphatidylserine synthase, putative; GC: 49.13%; Transmembrane domains: 6. Codon Adaptation Index (CAI): 0.783; Protein involved in transferase activity.
    
 0.923
SSA_1483
Sphingosine kinase (diacylglycerol kinase), putative; GC: 44.16%; Codon Adaptation Index (CAI): 0.786. Curator(s): J. Alves; Protein involved in protein kinase C activation.
    
 0.909
eep
Zinc metalloprotease, putative; GC: 47.33%; Transmembrane domains: 4. Codon Adaptation Index (CAI): 0.763; Protein involved in metal ion binding.
  
  
 0.901
proS
Prolyl-tRNA synthetase, putative; Catalyzes the attachment of proline to tRNA(Pro) in a two- step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and in [...]
  
    0.735
SSA_2071
Hypothetical protein; GC: 42.69%; Codon Adaptation Index (CAI): 0.713.
       0.668
yajC
Preprotein translocase subunit YajC, putative; GC: 45.24%; Transmembrane domains: 1. Codon Adaptation Index (CAI): 0.814. LipoP prediction: SpI. Curator(s): J. Alves.
       0.659
gdhA
NADP-specific glutamate dehydrogenase, putative; GC: 45.88%; Codon Adaptation Index (CAI): 0.789. Curator(s): T. Kitten; Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
      0.605
Your Current Organism:
Streptococcus sanguinis SK36
NCBI taxonomy Id: 388919
Other names: S. sanguinis SK36, Streptococcus sanguinis str. SK36, Streptococcus sanguinis strain SK36
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.