STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
uppSUndecaprenyl pyrophosphate synthetase, putative; Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids. (249 aa)    
Predicted Functional Partners:
cdsA
Phosphatidate cytidylyltransferase, putative; GC: 46.77%; Transmembrane domains: 7. Codon Adaptation Index (CAI): 0.785. SignalP prediction: Yes (prob. 0.672); Protein involved in nucleotidyltransferase activity; Belongs to the CDS family.
  
  
 0.991
ispA
Farnesyl diphosphate synthase, putative; GC: 46.8%; Codon Adaptation Index (CAI): 0.77. Curator(s): P. Xu; Belongs to the FPP/GGPP synthase family.
 
 
 0.970
bacA
Undecaprenyl-diphosphatase, putative; Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin; Belongs to the UppP family.
     
 0.967
proS
Prolyl-tRNA synthetase, putative; Catalyzes the attachment of proline to tRNA(Pro) in a two- step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and in [...]
  
  
 0.937
eep
Zinc metalloprotease, putative; GC: 47.33%; Transmembrane domains: 4. Codon Adaptation Index (CAI): 0.763; Protein involved in metal ion binding.
  
  
 0.887
ruvB
Holliday junction DNA helicase ruvB, putative; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing.
  
  
 0.792
rrf
Ribosome recycling factor, putative; Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another; Belongs to the RRF family.
  
  
 0.781
murD
UDP-N-acetylmuramoylalanine--D-glutamate ligase, putative; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family.
 
  
 0.777
nusA
N utilization substance protein A, putative; Participates in both transcription termination and antitermination.
  
    0.762
rimP
Conserved uncharacterized protein; Required for maturation of 30S ribosomal subunits. Belongs to the RimP family.
  
    0.742
Your Current Organism:
Streptococcus sanguinis SK36
NCBI taxonomy Id: 388919
Other names: S. sanguinis SK36, Streptococcus sanguinis str. SK36, Streptococcus sanguinis strain SK36
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