Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
SSA_2103Hypothetical protein; GC: 41.79%; Transmembrane domains: 1. Codon Adaptation Index (CAI): 0.727. LipoP prediction: SpI. SignalP prediction: Yes (prob. 0.815). (66 aa)    
Predicted Functional Partners:
SSA_2105
Conserved hypothetical protein; GC: 47.37%; Codon Adaptation Index (CAI): 0.765; Protein involved in porphyrin biosynthesis; Belongs to the uroporphyrinogen decarboxylase family.
       0.605
SSA_2102
Conserved uncharacterized protein; GC: 49.1%; Codon Adaptation Index (CAI): 0.767; Protein involved in porphyrin biosynthesis; Belongs to the uroporphyrinogen decarboxylase family.
       0.542
SSA_2101
Amino acid ABC transporter, periplasmic amino acid-binding protein, putative; GC: 44.29%; Transporter classification TC:3.A.1.3.13. Transmembrane domains: 1. Codon Adaptation Index (CAI): 0.811. LipoP prediction: SpI. SignalP prediction: Yes (prob. 0.998).
       0.522
Your Current Organism:
Streptococcus sanguinis SK36
NCBI taxonomy Id: 388919
Other names: S. sanguinis SK36, Streptococcus sanguinis str. SK36, Streptococcus sanguinis strain SK36
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