Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
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glmSGlucosamine--fructose-6-phosphate aminotransferase [isomerizing], putative; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source. (603 aa)    
Predicted Functional Partners:
glmM
Phosphoglucomutase/phosphomannomutase family protein, putative; Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; Belongs to the phosphohexose mutase family.
 
 
 0.982
nagA
N-acetylglucosamine-6-phosphate deacetylase, putative; GC: 48.7%; Codon Adaptation Index (CAI): 0.786; Protein involved in hydrolase activity.
    
 0.969
nagB
Glucosamine-6-phosphate deaminase, putative; Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion.
    
 0.965
glnA
Glutamine synthetase type 1, putative; GC: 45.06%; Codon Adaptation Index (CAI): 0.803. Curator(s): T. Kitten; Protein involved in ligase activity; Belongs to the glutamine synthetase family.
 
 
 0.959
pgi
Glucose-6-phosphate isomerase, putative; GC: 41.79%; Codon Adaptation Index (CAI): 0.77; Belongs to the GPI family.
  
 
 0.952
glmU
N-acetylglucosamine-1-phosphate uridyltransferase, putative; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain. In the C-terminal section; belongs to the transferase hexapeptide repea [...]
  
 0.946
pmi
Mannose-6-phosphate isomerase, putative; GC: 48.09%; Codon Adaptation Index (CAI): 0.796. Curator(s): X. Ge; Protein involved in zinc ion binding and isomerase activity; Belongs to the mannose-6-phosphate isomerase type 1 family.
     
 0.932
carB
Carbamoyl-phosphate synthase large chain, putative; GC: 49.5%; Codon Adaptation Index (CAI): 0.783; Protein involved in metal ion binding.
   
 0.922
purF
Glutamine phosphoribosylpyrophosphate amidotransferase, putative; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine; In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.
    
0.914
carA
Carbamoyl-phosphate synthase small chain, putative; GC: 48.24%; Transmembrane domains: 1. Codon Adaptation Index (CAI): 0.764; Protein involved in ligase activity; Belongs to the CarA family.
    
 0.913
Your Current Organism:
Streptococcus sanguinis SK36
NCBI taxonomy Id: 388919
Other names: S. sanguinis SK36, Streptococcus sanguinis str. SK36, Streptococcus sanguinis strain SK36
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