Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-expression
Experiments
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[Homology]
Score
gapAGlyceraldehyde 3-phosphate dehydrogenase, putative; GC: 42.36%; Codon Adaptation Index (CAI): 0.806; Protein involved in NAD binding; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. (335 aa)    
Predicted Functional Partners:
pgk
Phosphoglycerate kinase, putative; GC: 43.27%; Codon Adaptation Index (CAI): 0.793. Curator(s): P. Manque; Protein involved in transferase activity; Belongs to the phosphoglycerate kinase family.
 
 0.999
tpi
Triosephosphate isomerase, putative; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family.
 0.999
fba
Fructose-bisphosphate aldolase, putative; GC: 44.33%; Codon Adaptation Index (CAI): 0.763; Protein involved in fructose 1,6-bisphosphate metabolism.
  
 0.987
eno
Enolase, putative; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family.
 
 
 0.986
tkt
Transketolase, putative; Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.
  
 0.962
pgi
Glucose-6-phosphate isomerase, putative; GC: 41.79%; Codon Adaptation Index (CAI): 0.77; Belongs to the GPI family.
  
 0.962
pykF
Pyruvate kinase I, fructose-stimulated, putative; GC: 42.36%; Codon Adaptation Index (CAI): 0.802. Curator(s): L. Ozaki; Protein involved in transferase activity and glycolysis; Belongs to the pyruvate kinase family.
 
 
 0.942
gapN
NADP-dependent glyceraldehyde-3-phosphate dehydrogenase, putative; GC: 46.39%; Codon Adaptation Index (CAI): 0.791. Curator(s): X. Ge; Protein involved in oxidoreductase activity; Belongs to the aldehyde dehydrogenase family.
   
 
 0.940
gdh
Glucose-6-phosphate 1-dehydrogenase, putative; Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone.
  
 0.923
fusA
Elongation factor G, putative; Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 sub [...]
 
 
 0.916
Your Current Organism:
Streptococcus sanguinis SK36
NCBI taxonomy Id: 388919
Other names: S. sanguinis SK36, Streptococcus sanguinis str. SK36, Streptococcus sanguinis strain SK36
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