STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
rmuCDNA recombination protein RmuC, putative; GC: 46.7%; Codon Adaptation Index (CAI): 0.775. Curator(s): J. Alves; Protein involved in lipoprotein metabolism. (418 aa)    
Predicted Functional Partners:
cbf
Cmp-binding-factor 1, putative; GC: 45.82%; Codon Adaptation Index (CAI): 0.787; Protein involved in nucleic acid binding.
       0.855
SSA_2118
Thiamine pyrophosphokinase, putative; GC: 43.09%; Codon Adaptation Index (CAI): 0.788. SignalP prediction: Yes (prob. 0.452); Curator(s): J. Alves; Protein involved in thiamin diphosphate biosynthesis.
       0.855
rpe
Pentose-5-phosphate-3-epimerase, putative; GC: 46.06%; Codon Adaptation Index (CAI): 0.811; Protein involved in isomerase activity; Belongs to the ribulose-phosphate 3-epimerase family.
       0.855
SSA_2120
GTPase, putative; One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit; Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.
       0.849
purR
Transcriptional repressor of purine operon, putative; GC: 41.49%; Codon Adaptation Index (CAI): 0.761. Curator(s): J. Alves; Protein involved in negative regulation of purine base metabolism.
       0.759
pcrA
ATP-dependent DNA helicase, putative; GC: 48.01%; Codon Adaptation Index (CAI): 0.775. Curator(s): L. Ozaki; Protein involved in DNA repair.
    
 0.745
rpsL
30S ribosomal protein S12, putative; With S4 and S5 plays an important role in translational accuracy.
       0.632
rpsG
30S ribosomal protein S7, putative; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA; Belongs to the universal ribosomal protein uS7 family.
       0.622
rgpFc
Lipopolysaccharide biosynthesis protein, putative; GC: 41.77%; Codon Adaptation Index (CAI): 0.777; Protein involved in transferase activity.
  
     0.579
SSA_2113
Hypothetical protein; GC: 45.59%; Transmembrane domains: 1. Codon Adaptation Index (CAI): 0.773. SignalP prediction: Yes (prob. 0.975).
       0.551
Your Current Organism:
Streptococcus sanguinis SK36
NCBI taxonomy Id: 388919
Other names: S. sanguinis SK36, Streptococcus sanguinis str. SK36, Streptococcus sanguinis strain SK36
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.