STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
rnmVSmall primase-like protein (Toprim domain), putative; Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step. (198 aa)    
Predicted Functional Partners:
ksgA
Dimethyladenosine transferase, putative; Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.
  
  
 0.938
tatD
Conserved hypothetical protein; GC: 48.77%; Codon Adaptation Index (CAI): 0.756; Protein involved in hydrolase activity.
  
  
 0.884
SSA_2124
Dehydrogenase, eukaryotic-like, putative; GC: 38.48%; Codon Adaptation Index (CAI): 0.784. Curator(s): J. Alves; Protein involved in oxidoreductase activity.
     
 0.808
mrnC
Conserved hypothetical protein; Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc); Rnc processes 30S rRNA into smaller rRNA precursors; Belongs to the MrnC RNase family.
  
   
 0.620
cbf
Cmp-binding-factor 1, putative; GC: 45.82%; Codon Adaptation Index (CAI): 0.787; Protein involved in nucleic acid binding.
     
 0.619
SSA_2122
Conserved hypothetical protein; GC: 40.2%; Transmembrane domains: 4. Codon Adaptation Index (CAI): 0.746.
       0.559
rnhC
Ribonuclease HIII, putative; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
      
 0.552
labT
Conserved hypothetical protein; GC: 39.69%; Transmembrane domains: 10. Codon Adaptation Index (CAI): 0.766.
       0.533
elaC
Ribonuclease Z, putative; Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA; Belongs to the RNase Z family.
      
 0.490
rncS
Ribonuclease III, putative; Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
      
 0.468
Your Current Organism:
Streptococcus sanguinis SK36
NCBI taxonomy Id: 388919
Other names: S. sanguinis SK36, Streptococcus sanguinis str. SK36, Streptococcus sanguinis strain SK36
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