Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
tatDConserved hypothetical protein; GC: 48.77%; Codon Adaptation Index (CAI): 0.756; Protein involved in hydrolase activity. (256 aa)    
Predicted Functional Partners:
metS
Methionyl-tRNA synthetase, putative; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation; Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 2B subfamily.
 
 0.890
rnmV
Small primase-like protein (Toprim domain), putative; Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step.
  
  
 0.884
ksgA
Dimethyladenosine transferase, putative; Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.
  
  
 0.855
SSA_2124
Dehydrogenase, eukaryotic-like, putative; GC: 38.48%; Codon Adaptation Index (CAI): 0.784. Curator(s): J. Alves; Protein involved in oxidoreductase activity.
  
    0.800
SSA_2122
Conserved hypothetical protein; GC: 40.2%; Transmembrane domains: 4. Codon Adaptation Index (CAI): 0.746.
       0.555
tpi
Triosephosphate isomerase, putative; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family.
 
   
 0.539
labT
Conserved hypothetical protein; GC: 39.69%; Transmembrane domains: 10. Codon Adaptation Index (CAI): 0.766.
       0.533
iga
IgA-specific metalloendopeptidase; GC: 40.46%; Transmembrane domains: 3. Codon Adaptation Index (CAI): 0.765. LipoP prediction: SpI. SignalP prediction: Yes (prob. 1); Curator(s): J. Alves; Protein involved in hydrolase activity.
     
 0.532
SSA_1750
Extracellular nuclease, putative; GC: 46.58%; Transmembrane domains: 2. Codon Adaptation Index (CAI): 0.775. LipoP prediction: SpI. SignalP prediction: Yes (prob. 1); Helix-turn-helix prediction: AraC.
     
 0.500
polA
DNA polymerase I - 3'-5' exonuclease and polymerase domains, putative; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.
 
   
 0.495
Your Current Organism:
Streptococcus sanguinis SK36
NCBI taxonomy Id: 388919
Other names: S. sanguinis SK36, Streptococcus sanguinis str. SK36, Streptococcus sanguinis strain SK36
Server load: medium (42%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.