STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
SSA_21333-methyladenine DNA glycosylase, putative; GC: 36.9%; Codon Adaptation Index (CAI): 0.762. (186 aa)    
Predicted Functional Partners:
tag
GC: 40.54%; Codon Adaptation Index (CAI): 0.813; Protein involved in DNA-3-methyladenine glycosylase I activity.
  
  
 
0.906
SSA_2134
Conserved hypothetical protein; GC: 32.04%; Codon Adaptation Index (CAI): 0.749; Protein involved in FMN binding.
       0.762
guaB
Inosine-5'-monophosphate dehydrogenase, putative; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
    
  0.629
argR-2
Transcriptional repressor (arginine synthesis), putative; Regulates arginine biosynthesis genes.
  
    0.572
SSA_2135
Transcriptional repressor, DeoR family (possibly truncated), putative; GC: 33.33%; Codon Adaptation Index (CAI): 0.774. Curator(s): J. Alves; Protein involved in regulation of transcription, DNA-dependent.
       0.562
argR
Transcriptional repressor (arginine synthesis), putative; Regulates arginine biosynthesis genes.
  
    0.520
pbp2a
Penicillin-binding protein 2A, putative; GC: 47.78%; Transmembrane domains: 1. Codon Adaptation Index (CAI): 0.78; Protein involved in response to antibiotic.
   
    0.507
gmk
Guanylate kinase, putative; Essential for recycling GMP and indirectly, cGMP.
     
  0.500
polA
DNA polymerase I - 3'-5' exonuclease and polymerase domains, putative; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.
     
 0.476
Your Current Organism:
Streptococcus sanguinis SK36
NCBI taxonomy Id: 388919
Other names: S. sanguinis SK36, Streptococcus sanguinis str. SK36, Streptococcus sanguinis strain SK36
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