STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
SSA_2135Transcriptional repressor, DeoR family (possibly truncated), putative; GC: 33.33%; Codon Adaptation Index (CAI): 0.774. Curator(s): J. Alves; Protein involved in regulation of transcription, DNA-dependent. (205 aa)    
Predicted Functional Partners:
SSA_2134
Conserved hypothetical protein; GC: 32.04%; Codon Adaptation Index (CAI): 0.749; Protein involved in FMN binding.
 
     0.642
SSA_1436
Conserved hypothetical protein; GC: 35.92%; Codon Adaptation Index (CAI): 0.764. Helix-turn-helix prediction: AraC; Protein involved in regulation of transcription, DNA-dependent.
  
     0.634
SSA_0640
Conserved hypothetical protein; GC: 34.78%; Codon Adaptation Index (CAI): 0.773. Helix-turn-helix prediction: AraC. Curator(s): P. Xu; Protein involved in regulation of transcription, DNA-dependent.
  
     0.625
SSA_0667
Transcriptional regulator, putative; GC: 43.11%; Codon Adaptation Index (CAI): 0.75. Curator(s): P. Xu, J. Alves; Protein involved in regulation of transcription, DNA-dependent.
  
     0.596
rpoB
DNA-directed RNA polymerase I, beta chain (140 kDa subunit), putative; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
 
 0.563
rpoD
DNA-directed RNA polymerase, sigma subunit (sigma70/sigma32), putative; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.
    
   0.562
SSA_2133
3-methyladenine DNA glycosylase, putative; GC: 36.9%; Codon Adaptation Index (CAI): 0.762.
       0.562
rpoA
DNA-directed RNA polymerase, alpha chain, putative; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
   0.524
rpoC
DNA-directed RNA polymerase I, beta chain (160 kDa subunit), putative; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
   0.524
rpoZ
DNA-directed RNA polymerase, subunit K/omega, putative; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
    
   0.449
Your Current Organism:
Streptococcus sanguinis SK36
NCBI taxonomy Id: 388919
Other names: S. sanguinis SK36, Streptococcus sanguinis str. SK36, Streptococcus sanguinis strain SK36
Server load: low (22%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.