Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
SSA_2154Conserved uncharacterized protein; GC: 48.59%; Codon Adaptation Index (CAI): 0.749; Protein involved in lyase activity and carbon utilization. (165 aa)    
Predicted Functional Partners:
SSA_1098
Formate-nitrate transporter, putative; GC: 42.48%; Transporter classification TC:2.A.44.3.1. Transmembrane domains: 6. Codon Adaptation Index (CAI): 0.772.
  
    0.664
radA
ATP-dependent serine protease, putative; DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.
       0.570
SSA_2155
Conserved hypothetical protein; GC: 46.84%; Codon Adaptation Index (CAI): 0.801.
       0.556
SSA_2152
ABC-type transporter (uncharacterized), ATPase component, putative; GC: 45.85%; Transporter classification TC:3.A.1.12.4. Codon Adaptation Index (CAI): 0.736. Curator(s): J. Alves; Protein involved in nucleoside-triphosphatase activity.
       0.543
SSA_2153
ABC-type transporter (uncharacterized), permease component, putative; GC: 49.25%; Transporter classification TC:3.A.1.2.1. Transmembrane domains: 8. Codon Adaptation Index (CAI): 0.758. Curator(s): J. Alves; Belongs to the binding-protein-dependent transport system permease family.
       0.543
dut
Deoxyuridinetriphosphatase, putative; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.
     
 0.534
SSA_2159
Conserved hypothetical protein; GC: 47.09%; Codon Adaptation Index (CAI): 0.774.
  
    0.524
xpt
Xanthine phosphoribosyltransferase, putative; Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis.
   
    0.499
apt
Adenine phosphoribosyltransferase, putative; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
   
    0.499
purR
Transcriptional repressor of purine operon, putative; GC: 41.49%; Codon Adaptation Index (CAI): 0.761. Curator(s): J. Alves; Protein involved in negative regulation of purine base metabolism.
   
    0.499
Your Current Organism:
Streptococcus sanguinis SK36
NCBI taxonomy Id: 388919
Other names: S. sanguinis SK36, Streptococcus sanguinis str. SK36, Streptococcus sanguinis strain SK36
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