Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Neighborhood
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Co-occurrence
Co-expression
Experiments
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[Homology]
Score
SSA_2159Conserved hypothetical protein; GC: 47.09%; Codon Adaptation Index (CAI): 0.774. (171 aa)    
Predicted Functional Partners:
dut
Deoxyuridinetriphosphatase, putative; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.
       0.855
radA
ATP-dependent serine protease, putative; DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.
       0.639
SSA_2158
Methyltransferase, putative; GC: 40.76%; Codon Adaptation Index (CAI): 0.766. Helix-turn-helix prediction: AraC; Protein involved in transferase activity.
       0.613
SSA_2161
NTP pyrophosphohydrolases including oxidative damage repair enzymes, putative; GC: 41.11%; Codon Adaptation Index (CAI): 0.772; Protein involved in hydrolase activity.
       0.550
SSA_2154
Conserved uncharacterized protein; GC: 48.59%; Codon Adaptation Index (CAI): 0.749; Protein involved in lyase activity and carbon utilization.
  
    0.524
SSA_1705
Conserved hypothetical protein; GC: 40.79%; Transmembrane domains: 2. Codon Adaptation Index (CAI): 0.791. SignalP prediction: Yes (prob. 0.473).
  
     0.417
SSA_2162
Hypothetical protein; GC: 32.64%; Codon Adaptation Index (CAI): 0.765.
       0.413
cobQ-2
Cobyric acid synthase, putative; Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. Belongs to the CobB/CobQ family. CobQ subfamily.
  
    0.406
Your Current Organism:
Streptococcus sanguinis SK36
NCBI taxonomy Id: 388919
Other names: S. sanguinis SK36, Streptococcus sanguinis str. SK36, Streptococcus sanguinis strain SK36
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