STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
galUGlucose-1-phosphate uridylyltransferase, putative; GC: 45.83%; Codon Adaptation Index (CAI): 0.796. LipoP prediction: SpI. SignalP prediction: Yes (prob. 0.993); Helix-turn-helix prediction: AraC; Protein involved in nucleotidyltransferase activity. (319 aa)    
Predicted Functional Partners:
galE
UDP-glucose 4-epimerase, putative; GC: 47.8%; Transmembrane domains: 1. Codon Adaptation Index (CAI): 0.782; Protein involved in NAD binding; Belongs to the NAD(P)-dependent epimerase/dehydratase family.
 
  
 0.981
pgm
Phosphoglucomutase; GC: 44.5%; Codon Adaptation Index (CAI): 0.821. Helix-turn-helix prediction: AraC.
 
  
 0.976
galT
Galactose-1-phosphate-uridylyltransferase, putative; GC: 48.52%; Codon Adaptation Index (CAI): 0.774.
     
 0.964
glmU
N-acetylglucosamine-1-phosphate uridyltransferase, putative; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain. In the C-terminal section; belongs to the transferase hexapeptide repea [...]
 
  
 0.927
rmlA
Glucose-1-phosphate thymidylytransferase, putative; Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis. Belongs to the glucose-1-phosphate thymidylyltransferase family.
  
 
0.924
glgC
Glucose-1-phosphate adenylyltransferase, putative; Involved in the biosynthesis of ADP-glucose, a building block required for the elongation reactions to produce glycogen. Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc; Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.
     
 0.921
pulA
Type II secretory pathway, pullulanase PulA glycosidase, putative; GC: 47.76%; Codon Adaptation Index (CAI): 0.759; Belongs to the glycosyl hydrolase 13 family.
     
 0.919
glgD
Glycogen biosynthesis protein GlgD, putative; GC: 42.89%; Codon Adaptation Index (CAI): 0.775. Curator(s): X. Ge; Protein involved in nucleotidyltransferase activity.
     
 0.909
glgP
Glycogen phosphorylase, putative; Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties.
     
 0.906
malP
Maltodextrin phosphorylase, putative; Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties.
     
 0.906
Your Current Organism:
Streptococcus sanguinis SK36
NCBI taxonomy Id: 388919
Other names: S. sanguinis SK36, Streptococcus sanguinis str. SK36, Streptococcus sanguinis strain SK36
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