Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
SSA_2170Conserved hypothetical protein; GC: 41.37%; Transmembrane domains: 6. Codon Adaptation Index (CAI): 0.774. SignalP prediction: Yes (prob. 0.942). (227 aa)    
Predicted Functional Partners:
SSA_2171
Conserved hypothetical protein; GC: 44.88%; Codon Adaptation Index (CAI): 0.783; Protein involved in 5-formyltetrahydrofolate cyclo-ligase activity and metabolism; Belongs to the 5-formyltetrahydrofolate cyclo-ligase family.
  
  
 0.944
hipO
Aminoacylase/N-acyl-L-amino acid amidohydrolase/hippurate hydrolase, putative; Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate.
       0.826
tatA
TatA, sec-independent protein secretion pathway component, putative; GC: 42.86%; Transmembrane domains: 1. Codon Adaptation Index (CAI): 0.769. Curator(s): J. Alves.
   
 
 0.747
dapD
2,3,4,5-tetrahydropyridine-2-carboxylate N-succinyltransferase, putative; Catalyzes the transfer of an acetyl group from acetyl-CoA to tetrahydrodipicolinate.
       0.725
SSA_1965
Stomatin/prohibitin-like membrane protease subunits, putative; GC: 42.55%; Transmembrane domains: 1. Codon Adaptation Index (CAI): 0.768.
   
 0.669
SSA_0257
N-acetylmuramidase/lysin, putative; GC: 48.35%; Transmembrane domains: 1. Codon Adaptation Index (CAI): 0.782. LipoP prediction: SpI. SignalP prediction: Yes (prob. 1); Curator(s): P. Manque; Protein involved in cell wall catabolism.
   
   0.564
SSA_0860
N-acetylmuramidase/lysin, putative; GC: 45.85%; Codon Adaptation Index (CAI): 0.787. Curator(s): L. Ozaki; Protein involved in cell wall catabolism.
   
   0.564
rimP
Conserved uncharacterized protein; Required for maturation of 30S ribosomal subunits. Belongs to the RimP family.
      
 0.502
groEL
60 kDa chaperonin; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions.
  
  
 0.486
SSA_0646
Conserved hypothetical protein; GC: 38.36%; Codon Adaptation Index (CAI): 0.764. Curator(s): P. Xu.
     
 0.468
Your Current Organism:
Streptococcus sanguinis SK36
NCBI taxonomy Id: 388919
Other names: S. sanguinis SK36, Streptococcus sanguinis str. SK36, Streptococcus sanguinis strain SK36
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