Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-occurrence
Co-expression
Experiments
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[Homology]
Score
pgiGlucose-6-phosphate isomerase, putative; GC: 41.79%; Codon Adaptation Index (CAI): 0.77; Belongs to the GPI family. (460 aa)    
Predicted Functional Partners:
tpi
Triosephosphate isomerase, putative; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family.
  
 0.992
pfk
6-phosphofructokinase, putative; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
  
 0.988
eno
Enolase, putative; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family.
  
 0.986
pgm
Phosphoglucomutase; GC: 44.5%; Codon Adaptation Index (CAI): 0.821. Helix-turn-helix prediction: AraC.
 
 
 0.980
tkt
Transketolase, putative; Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.
  
 0.975
pmi
Mannose-6-phosphate isomerase, putative; GC: 48.09%; Codon Adaptation Index (CAI): 0.796. Curator(s): X. Ge; Protein involved in zinc ion binding and isomerase activity; Belongs to the mannose-6-phosphate isomerase type 1 family.
 
 
 0.973
gdh
Glucose-6-phosphate 1-dehydrogenase, putative; Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone.
  
 
 0.973
pykF
Pyruvate kinase I, fructose-stimulated, putative; GC: 42.36%; Codon Adaptation Index (CAI): 0.802. Curator(s): L. Ozaki; Protein involved in transferase activity and glycolysis; Belongs to the pyruvate kinase family.
  
 0.968
glcK
Glucokinase, putative; GC: 46.15%; Codon Adaptation Index (CAI): 0.799; Protein involved in kinase activity and glycolysis.
 
 
 0.968
fba
Fructose-bisphosphate aldolase, putative; GC: 44.33%; Codon Adaptation Index (CAI): 0.763; Protein involved in fructose 1,6-bisphosphate metabolism.
  
 0.963
Your Current Organism:
Streptococcus sanguinis SK36
NCBI taxonomy Id: 388919
Other names: S. sanguinis SK36, Streptococcus sanguinis str. SK36, Streptococcus sanguinis strain SK36
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