Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
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Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
SSA_2189Conserved hypothetical protein; GC: 47.86%; Codon Adaptation Index (CAI): 0.778; Protein involved in ADP-ribosyl-[dinitrogen reductase] hydrolase activity and hydrolase activity. (272 aa)    
Predicted Functional Partners:
hslO
33 kDa chaperonin, putative; Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress.
       0.538
nifR
Conserved uncharacterized protein; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines; Belongs to the dus family.
       0.527
nadR
ATPase/kinase, putative; GC: 45.33%; Codon Adaptation Index (CAI): 0.804. Possibly involved in NAD metabolism. Curator(s): J. Alves; Protein involved in nucleotidyltransferase activity and regulation of transcription.
       0.449
kptA
RNA:NAD 2'-phosphotransferase, putative; Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP-ribose 1''-2''- cyclic phosphate (APPR>P). May function as an ADP-ribosylase.
 
   
 0.439
SSA_2193
ADP-ribose pyrophosphatase, putative; GC: 47.38%; Codon Adaptation Index (CAI): 0.748. Curator(s): J. Alves; Protein involved in hydrolase activity.
 
     0.431
Your Current Organism:
Streptococcus sanguinis SK36
NCBI taxonomy Id: 388919
Other names: S. sanguinis SK36, Streptococcus sanguinis str. SK36, Streptococcus sanguinis strain SK36
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