Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
SSA_2194Nicotinamide mononucleotide transporter, putative; GC: 47.43%; Transporter classification TC:9.A.4.1.1. Transmembrane domains: 4. Codon Adaptation Index (CAI): 0.76. Curator(s): J. Alves. (271 aa)    
Predicted Functional Partners:
nadR
ATPase/kinase, putative; GC: 45.33%; Codon Adaptation Index (CAI): 0.804. Possibly involved in NAD metabolism. Curator(s): J. Alves; Protein involved in nucleotidyltransferase activity and regulation of transcription.
 
   
 0.965
SSA_2193
ADP-ribose pyrophosphatase, putative; GC: 47.38%; Codon Adaptation Index (CAI): 0.748. Curator(s): J. Alves; Protein involved in hydrolase activity.
     
 0.645
crpA
CshA-like fibrillar surface protein A; GC: 46.68%; Transmembrane domains: 1. Codon Adaptation Index (CAI): 0.801. LipoP prediction: SpI. SignalP prediction: Yes (prob. 1); Curator(s): L. Ozaki, J. Alves; Protein involved in calcium ion binding and pathogenesis.
  
    0.544
crpC
CshA-like fibrillar surface protein C; GC: 46.28%; Codon Adaptation Index (CAI): 0.794. LipoP prediction: SpI. SignalP prediction: Yes (prob. 1); Curator(s): T. Kitten, J. Alves; Protein involved in pathogenesis.
  
    0.538
crpB
CshA-like fibrillar surface protein B; GC: 46.38%; Codon Adaptation Index (CAI): 0.797. LipoP prediction: SpI. SignalP prediction: Yes (prob. 1); Curator(s): T. Kitten, J. Alves; Protein involved in pathogenesis.
  
    0.536
SSA_1682
Conserved hypothetical protein; GC: 45.77%; Transmembrane domains: 8. Codon Adaptation Index (CAI): 0.733.
  
     0.470
SSA_1705
Conserved hypothetical protein; GC: 40.79%; Transmembrane domains: 2. Codon Adaptation Index (CAI): 0.791. SignalP prediction: Yes (prob. 0.473).
  
     0.458
SSA_1274
Hypothetical protein; GC: 39.32%; Codon Adaptation Index (CAI): 0.804. LipoP prediction: SpI. SignalP prediction: Yes (prob. 1).
  
     0.434
SSA_1183
Conserved hypothetical protein; GC: 42.8%; Codon Adaptation Index (CAI): 0.794.
  
     0.429
SSA_2196
Conserved uncharacterized protein; GC: 44.03%; Codon Adaptation Index (CAI): 0.844. LipoP prediction: SpII. SignalP prediction: Yes (prob. 1); Curator(s): J. Alves.
       0.423
Your Current Organism:
Streptococcus sanguinis SK36
NCBI taxonomy Id: 388919
Other names: S. sanguinis SK36, Streptococcus sanguinis str. SK36, Streptococcus sanguinis strain SK36
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