STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
pbp2aPenicillin-binding protein 2A, putative; GC: 47.78%; Transmembrane domains: 1. Codon Adaptation Index (CAI): 0.78; Protein involved in response to antibiotic. (742 aa)    
Predicted Functional Partners:
pbpX
Penicillin-binding protein 2X, putative; GC: 45.35%; Transmembrane domains: 1. Codon Adaptation Index (CAI): 0.791. LipoP prediction: SpI. SignalP prediction: Yes (prob. 0.924); Protein involved in cell division and cell wall biosynthesis (sensu Bacteria).
 
 
 0.992
pbp2b
Penicillin-binding protein 2B, putative; GC: 48.57%; Transmembrane domains: 1. Codon Adaptation Index (CAI): 0.767. LipoP prediction: SpI. SignalP prediction: Yes (prob. 0.995); Curator(s): P. Xu; Protein involved in penicillin binding and cell wall biosynthesis (sensu Bacteria).
 
 
 0.987
pbp3
Penicillin-binding protein 3, putative; GC: 45.63%; Codon Adaptation Index (CAI): 0.763. LipoP prediction: SpI. SignalP prediction: Yes (prob. 1); Helix-turn-helix prediction: AraC; Protein involved in proteolysis; Belongs to the peptidase S11 family.
   
 
 0.949
mrcB
Membrane carboxypeptidase (penicillin-binding protein), putative; GC: 46.63%; Transmembrane domains: 1. Codon Adaptation Index (CAI): 0.778. Curator(s): M. Serrano, J. Alves.
  
  
0.926
pbp1A
Penicillin-binding protein 1A, putative; GC: 45.28%; Transmembrane domains: 1. Codon Adaptation Index (CAI): 0.775. LipoP prediction: SpII. SignalP prediction: Yes (prob. 0.699); Protein involved in response to antibiotic.
  
  
0.926
SSA_2014
D-alanyl-D-alanine carboxypeptidase, putative; GC: 47.28%; Transmembrane domains: 1. Codon Adaptation Index (CAI): 0.791. LipoP prediction: SpI. SignalP prediction: Yes (prob. 1); Protein involved in dipeptidase activity, hydrolase activity and peptidase activity.
     
 0.910
gpsB
Conserved DivIVA-like protein, putative; Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation.
   
 
 0.907
ftsW
Cell division protein FtsW, putative; GC: 44.2%; Transporter classification TC:9.B.3.1.3. Transmembrane domains: 8. Codon Adaptation Index (CAI): 0.729. SignalP prediction: Yes (prob. 0.95); Protein involved in cell division; Belongs to the SEDS family.
  
 
 
 0.905
rodA
Rod shape determining protein (cell-cycle protein), putative; GC: 44.77%; Transporter classification TC:9.B.3.1.3. Transmembrane domains: 10. Codon Adaptation Index (CAI): 0.775. Curator(s): L. Ozaki, J. Alves; Protein involved in cell division; Belongs to the SEDS family.
  
 
 
 0.903
SSA_1277
D-alanyl-D-alanine carboxypeptidase; GC: 42.91%; Codon Adaptation Index (CAI): 0.784. LipoP prediction: SpII. SignalP prediction: Yes (prob. 1); Curator(s): J. Alves; Protein involved in carboxypeptidase activity, peptidase activity and regulation of transcription.
     
 0.900
Your Current Organism:
Streptococcus sanguinis SK36
NCBI taxonomy Id: 388919
Other names: S. sanguinis SK36, Streptococcus sanguinis str. SK36, Streptococcus sanguinis strain SK36
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.