STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
nrdGOrganic radical activating chaperone, putative; Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine. (201 aa)    
Predicted Functional Partners:
nrdD
Ribonucleotide reductase, class III, anaerobic, putative; GC: 48.63%; Codon Adaptation Index (CAI): 0.764; Protein involved in ribonucleoside-triphosphate reductase activity and metabolism.
 
 
 0.993
SSA_1190
Conserved uncharacterized protein; GC: 42.48%; Codon Adaptation Index (CAI): 0.815.
 
 
 0.879
SSA_2227
Acetyl transferase, putative; GC: 46.7%; Codon Adaptation Index (CAI): 0.758; Protein involved in N-acetyltransferase activity and transferase activity.
       0.805
SSA_2228
Acetyltransferase (GNAT) family, putative; GC: 49.4%; Codon Adaptation Index (CAI): 0.741. Curator(s): J. Alves; Protein involved in N-acetyltransferase activity and transferase activity.
       0.805
SSA_0242
Conserved hypothetical protein; Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.
  
  
 0.721
guaA
GMP synthase [glutamine-hydrolyzing], putative; Catalyzes the synthesis of GMP from XMP.
     
 0.694
rnh
Ribonuclease HII, putative; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids; Belongs to the RNase HII family.
     
 0.648
SSA_2231
Heme/copper-type cytochrome/quinol oxidases, subunit 1, putative; GC: 45.16%; Transmembrane domains: 10. Codon Adaptation Index (CAI): 0.783.
       0.630
tyrS
Tyrosyl-tRNA synthetase 1, putative; Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two- step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr); Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily.
      
 0.629
nadD
Nicotinate-nucleotide adenylyltransferase, putative; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).
     
 0.623
Your Current Organism:
Streptococcus sanguinis SK36
NCBI taxonomy Id: 388919
Other names: S. sanguinis SK36, Streptococcus sanguinis str. SK36, Streptococcus sanguinis strain SK36
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