STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SSA_2252Conserved hypothetical protein; GC: 41.78%; Transmembrane domains: 5. Codon Adaptation Index (CAI): 0.745. (145 aa)    
Predicted Functional Partners:
ruvA
Holliday junction DNA helicase ruvA, putative; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB.
 
     0.573
tag
GC: 40.54%; Codon Adaptation Index (CAI): 0.813; Protein involved in DNA-3-methyladenine glycosylase I activity.
       0.505
lytB
S-layer protein/ peptidoglycan endo-beta-N-acetylglucosaminidase, putative; GC: 45%; Transmembrane domains: 1. Codon Adaptation Index (CAI): 0.771. LipoP prediction: SpI. SignalP prediction: Yes (prob. 1); Protein involved in peptidoglycan catabolism.
  
 
   0.432
Your Current Organism:
Streptococcus sanguinis SK36
NCBI taxonomy Id: 388919
Other names: S. sanguinis SK36, Streptococcus sanguinis str. SK36, Streptococcus sanguinis strain SK36
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