STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
SSA_2255Transcriptional regulator, XRE family, putative; GC: 40.24%; Transmembrane domains: 2. Codon Adaptation Index (CAI): 0.782. Curator(s): J. Alves; Protein involved in DNA binding. (168 aa)    
Predicted Functional Partners:
SSA_2256
Hypothetical protein; GC: 43.12%; Transmembrane domains: 3. Codon Adaptation Index (CAI): 0.756.
       0.777
SSA_0172
Transcriptional regulator, XRE family, putative; GC: 41.5%; Codon Adaptation Index (CAI): 0.745. Curator(s): M. Serrano, J. Alves; Protein involved in DNA binding, serine-type peptidase activity and regulation of transcription, DNA-dependent.
  
    0.721
ruvA
Holliday junction DNA helicase ruvA, putative; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB.
       0.518
tag
GC: 40.54%; Codon Adaptation Index (CAI): 0.813; Protein involved in DNA-3-methyladenine glycosylase I activity.
       0.513
Your Current Organism:
Streptococcus sanguinis SK36
NCBI taxonomy Id: 388919
Other names: S. sanguinis SK36, Streptococcus sanguinis str. SK36, Streptococcus sanguinis strain SK36
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