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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
malRLactose operon transcriptional repressor, LacI family, putative; GC: 46.95%; Codon Adaptation Index (CAI): 0.754. Helix-turn-helix prediction: LysRAraC. Curator(s): J. Alves; Protein involved in regulation of transcription and regulation of transcription, DNA-dependent. (327 aa)    
Predicted Functional Partners:
pulA
Type II secretory pathway, pullulanase PulA glycosidase, putative; GC: 47.76%; Codon Adaptation Index (CAI): 0.759; Belongs to the glycosyl hydrolase 13 family.
     
 0.709
malP
Maltodextrin phosphorylase, putative; Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties.
     
 0.687
glgP
Glycogen phosphorylase, putative; Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties.
     
 0.679
malX
Maltose/maltodextrin ABC transporter, sugar-binding protein MalX, putative; GC: 42.32%; Transporter classification TC:3.A.1.1.6. Codon Adaptation Index (CAI): 0.796. LipoP prediction: SpII. SignalP prediction: Yes (prob. 1); Protein involved in transport.
  
  
 0.661
malQ
4-alpha-glucanotransferase, putative; GC: 46.49%; Codon Adaptation Index (CAI): 0.81. Helix-turn-helix prediction: AraC; Protein involved in transferase activity.
     
 0.653
glcK
Glucokinase, putative; GC: 46.15%; Codon Adaptation Index (CAI): 0.799; Protein involved in kinase activity and glycolysis.
     
 0.617
ptsG
PTS system glucose-specific EIIC BA component (EIICBA-Glc) (EII- Glc/EIII-Glc), putative; GC: 43.23%; Transporter classification TC:4.A.1.1.2. Transmembrane domains: 9. Codon Adaptation Index (CAI): 0.798.
  
  
 0.617
ptsH
Histidine-containing phosphocarrier protein of the PTS, putative; GC: 41.67%; Transporter classification TC:8.A.8.1.1. Codon Adaptation Index (CAI): 0.817. Curator(s): X. Ge; Protein involved in transferase activity and phosphoenolpyruvate-dependent sugar phosphotransferase system.
   
 
 0.609
guaB
Inosine-5'-monophosphate dehydrogenase, putative; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
    
 
 0.505
guaA
GMP synthase [glutamine-hydrolyzing], putative; Catalyzes the synthesis of GMP from XMP.
    
   0.502
Your Current Organism:
Streptococcus sanguinis SK36
NCBI taxonomy Id: 388919
Other names: S. sanguinis SK36, Streptococcus sanguinis str. SK36, Streptococcus sanguinis strain SK36
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