Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
SSA_2269Conserved hypothetical protein; GC: 44.44%; Transmembrane domains: 5. Codon Adaptation Index (CAI): 0.773. LipoP prediction: SpI. SignalP prediction: Yes (prob. 0.998). (311 aa)    
Predicted Functional Partners:
aspRS2
Aspartyl-tRNA synthetase, putative; Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction: L-aspartate is first activated by ATP to form Asp- AMP and then transferred to the acceptor end of tRNA(Asp). Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
       0.855
SSA_1723
Conserved hypothetical protein; GC: 43.47%; Transmembrane domains: 5. Codon Adaptation Index (CAI): 0.759.
 
    
0.578
SSA_2271
Conserved hypothetical protein; GC: 45.54%; Transmembrane domains: 2. Codon Adaptation Index (CAI): 0.748. SignalP prediction: Yes (prob. 0.791); Curator(s): T. Kitten.
       0.537
hisS
Histidyl-tRNA synthetase, putative; GC: 47.23%; Codon Adaptation Index (CAI): 0.785; Protein involved in histidyl-tRNA aminoacylation.
       0.527
nrdI
Ribonucleotide reductase (NrdI family protein), putative; GC: 43.56%; Codon Adaptation Index (CAI): 0.824. Curator(s): J. Alves; Belongs to the NrdI family.
       0.449
Your Current Organism:
Streptococcus sanguinis SK36
NCBI taxonomy Id: 388919
Other names: S. sanguinis SK36, Streptococcus sanguinis str. SK36, Streptococcus sanguinis strain SK36
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