Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
SSA_2371Zn-dependent peptidase, putative; GC: 38.25%; Codon Adaptation Index (CAI): 0.816. Curator(s): J. Alves; Protein involved in peptidase activity. (419 aa)    
Predicted Functional Partners:
SSA_2370
Zn-dependemt peptidase (insulinase), M16 family, putative; GC: 39.04%; Codon Adaptation Index (CAI): 0.807. Curator(s): J. Alves.
 
  
 0.990
uncH
Proton-translocating ATPase, F1 sector, delta subunit, putative; F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation; Belongs to the ATPase delta chain family.
   
 0.819
uncA
Proton-translocating ATPase, F1 sector, alpha subunit, putative; Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit. Belongs to the ATPase alpha/beta chains family.
   
 0.807
SSA_2369
Conserved hypothetical protein; GC: 41.64%; Transmembrane domains: 1. Codon Adaptation Index (CAI): 0.759.
       0.800
pgsA
CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase, putative; GC: 37.41%; Transmembrane domains: 3. Codon Adaptation Index (CAI): 0.785. SignalP prediction: Yes (prob. 0.554); Protein involved in transferase activity; Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
  
  
 0.791
ecfT
Cobalt transport protein cbiQ, putative; Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates.
       0.784
ecfA2
ABC-type cobalt transport system, ATPase component, putative; ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates.
       0.784
stpA
ABC-type cobalt transport system, ATPase component, putative; ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates.
       0.784
SSA_2372
Conserved hypothetical protein; GC: 37.59%; Codon Adaptation Index (CAI): 0.798. Curator(s): J. Alves; (possible S4-like RNA-binding protein).
  
    0.724
recF
DNA replication and repair protein recF, putative; The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP.
  
    0.724
Your Current Organism:
Streptococcus sanguinis SK36
NCBI taxonomy Id: 388919
Other names: S. sanguinis SK36, Streptococcus sanguinis str. SK36, Streptococcus sanguinis strain SK36
Server load: medium (52%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.