node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
PNK_0194 | PNK_0247 | PNK_0194 | PNK_0247 | Sua5/YciO/YrdC/YwlC family protein; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. | Conserved hypothetical protein; Predicted ATPase or kinase. | 0.711 |
PNK_0194 | PNK_1900 | PNK_0194 | PNK_1900 | Sua5/YciO/YrdC/YwlC family protein; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. | Putative peptidase. | 0.687 |
PNK_0194 | gcp | PNK_0194 | PNK_0973 | Sua5/YciO/YrdC/YwlC family protein; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. | O-sialoglycoprotein endopeptidase; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction; Belongs to the KAE1 / TsaD family. | 0.708 |
PNK_0246 | PNK_0247 | PNK_0246 | PNK_0247 | Conserved hypothetical protein. | Conserved hypothetical protein; Predicted ATPase or kinase. | 0.640 |
PNK_0246 | dnaq1 | PNK_0246 | PNK_0249 | Conserved hypothetical protein. | DNA polymerase III epsilon chain. | 0.640 |
PNK_0246 | engB | PNK_0246 | PNK_0248 | Conserved hypothetical protein. | GTP-binding protein EngB; Necessary for normal cell division and for the maintenance of normal septation; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family. | 0.640 |
PNK_0246 | pdxS | PNK_0246 | PNK_0250 | Conserved hypothetical protein. | Pyridoxal biosynthesis lyase; Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5- phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively. Belongs to the PdxS/SNZ family. | 0.615 |
PNK_0246 | pdxT | PNK_0246 | PNK_0251 | Conserved hypothetical protein. | Glutamine amidotransferase; Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS. | 0.611 |
PNK_0247 | PNK_0194 | PNK_0247 | PNK_0194 | Conserved hypothetical protein; Predicted ATPase or kinase. | Sua5/YciO/YrdC/YwlC family protein; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. | 0.711 |
PNK_0247 | PNK_0246 | PNK_0247 | PNK_0246 | Conserved hypothetical protein; Predicted ATPase or kinase. | Conserved hypothetical protein. | 0.640 |
PNK_0247 | PNK_1900 | PNK_0247 | PNK_1900 | Conserved hypothetical protein; Predicted ATPase or kinase. | Putative peptidase. | 0.968 |
PNK_0247 | dnaq1 | PNK_0247 | PNK_0249 | Conserved hypothetical protein; Predicted ATPase or kinase. | DNA polymerase III epsilon chain. | 0.808 |
PNK_0247 | engB | PNK_0247 | PNK_0248 | Conserved hypothetical protein; Predicted ATPase or kinase. | GTP-binding protein EngB; Necessary for normal cell division and for the maintenance of normal septation; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family. | 0.826 |
PNK_0247 | gcp | PNK_0247 | PNK_0973 | Conserved hypothetical protein; Predicted ATPase or kinase. | O-sialoglycoprotein endopeptidase; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction; Belongs to the KAE1 / TsaD family. | 0.868 |
PNK_0247 | nnrD | PNK_0247 | PNK_0071 | Conserved hypothetical protein; Predicted ATPase or kinase. | YjeF family protein; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epim [...] | 0.750 |
PNK_0247 | pdxS | PNK_0247 | PNK_0250 | Conserved hypothetical protein; Predicted ATPase or kinase. | Pyridoxal biosynthesis lyase; Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5- phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively. Belongs to the PdxS/SNZ family. | 0.778 |
PNK_0247 | pdxT | PNK_0247 | PNK_0251 | Conserved hypothetical protein; Predicted ATPase or kinase. | Glutamine amidotransferase; Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS. | 0.776 |
PNK_0247 | pitA | PNK_0247 | PNK_2304 | Conserved hypothetical protein; Predicted ATPase or kinase. | Phosphate transporter. | 0.560 |
PNK_1900 | PNK_0194 | PNK_1900 | PNK_0194 | Putative peptidase. | Sua5/YciO/YrdC/YwlC family protein; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. | 0.687 |
PNK_1900 | PNK_0247 | PNK_1900 | PNK_0247 | Putative peptidase. | Conserved hypothetical protein; Predicted ATPase or kinase. | 0.968 |