STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PNK_0405Conserved hypothetical protein; Predicted RNA-binding protein (contains KH domain); Belongs to the UPF0109 family. (82 aa)    
Predicted Functional Partners:
rpsP
30S ribosomal protein S16; Belongs to the bacterial ribosomal protein bS16 family.
  
  
 0.980
rplS
50S ribosomal protein L19; This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.
 
    0.933
rpsD
30S ribosomal protein S4; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
   
    0.901
rpsO
30S ribosomal protein S15; Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
   
    0.900
rplT
50S ribosomal protein L20; Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.
  
    0.865
rpsR
30S ribosomal protein S18; Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit; Belongs to the bacterial ribosomal protein bS18 family.
   
    0.841
rpmE2
50S ribosomal protein L31 type B.
   
    0.822
rpsT
30S ribosomal protein S20; Binds directly to 16S ribosomal RNA.
   
    0.817
rpsI
30S ribosomal protein S9; Belongs to the universal ribosomal protein uS9 family.
  
    0.811
rplL
50S ribosomal protein L7/L12; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation; Belongs to the bacterial ribosomal protein bL12 family.
   
    0.793
Your Current Organism:
Protochlamydia naegleriophila
NCBI taxonomy Id: 389348
Other names: C. Protochlamydia naegleriophila, Candidatus Protochlamydia naegleriophila, strain KNic
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.