node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
cmk | nusA | PNK_0453 | PNK_1362 | Cytidylate kinase. | Transcription elongation protein nusA; Participates in both transcription termination and antitermination. | 0.752 |
cmk | ribF | PNK_0453 | PNK_1366 | Cytidylate kinase. | Putative riboflavin kinase/FMN adenylyltransferase; Belongs to the ribF family. | 0.757 |
coaD | ribA | PNK_2302 | PNK_1224 | Phosphopantetheine adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. | Putative 3,4-dihydroxy-2-butanone 4-phosphate synthase/GTP cyclohydrolase II; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the C-terminal section; belongs to the GTP cyclohydrolase II family. | 0.490 |
coaD | ribD | PNK_2302 | PNK_0848 | Phosphopantetheine adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. | Diaminohydroxyphosphoribosylaminopyrimidine deaminase; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | 0.493 |
coaD | ribF | PNK_2302 | PNK_1366 | Phosphopantetheine adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. | Putative riboflavin kinase/FMN adenylyltransferase; Belongs to the ribF family. | 0.658 |
nusA | cmk | PNK_1362 | PNK_0453 | Transcription elongation protein nusA; Participates in both transcription termination and antitermination. | Cytidylate kinase. | 0.752 |
nusA | rbfA | PNK_1362 | PNK_1364 | Transcription elongation protein nusA; Participates in both transcription termination and antitermination. | Ribosome-binding factor A; One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA. | 0.863 |
nusA | ribF | PNK_1362 | PNK_1366 | Transcription elongation protein nusA; Participates in both transcription termination and antitermination. | Putative riboflavin kinase/FMN adenylyltransferase; Belongs to the ribF family. | 0.677 |
nusA | truB | PNK_1362 | PNK_1365 | Transcription elongation protein nusA; Participates in both transcription termination and antitermination. | tRNA pseudouridine synthase B; Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs; Belongs to the pseudouridine synthase TruB family. Type 1 subfamily. | 0.967 |
phnP | ribF | PNK_0859 | PNK_1366 | Putative metal-dependent hydrolase, beta-lactamase superfamily I. | Putative riboflavin kinase/FMN adenylyltransferase; Belongs to the ribF family. | 0.583 |
rbfA | nusA | PNK_1364 | PNK_1362 | Ribosome-binding factor A; One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA. | Transcription elongation protein nusA; Participates in both transcription termination and antitermination. | 0.863 |
rbfA | ribF | PNK_1364 | PNK_1366 | Ribosome-binding factor A; One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA. | Putative riboflavin kinase/FMN adenylyltransferase; Belongs to the ribF family. | 0.672 |
rbfA | truB | PNK_1364 | PNK_1365 | Ribosome-binding factor A; One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA. | tRNA pseudouridine synthase B; Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs; Belongs to the pseudouridine synthase TruB family. Type 1 subfamily. | 0.994 |
ribA | coaD | PNK_1224 | PNK_2302 | Putative 3,4-dihydroxy-2-butanone 4-phosphate synthase/GTP cyclohydrolase II; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the C-terminal section; belongs to the GTP cyclohydrolase II family. | Phosphopantetheine adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. | 0.490 |
ribA | ribC | PNK_1224 | PNK_1223 | Putative 3,4-dihydroxy-2-butanone 4-phosphate synthase/GTP cyclohydrolase II; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the C-terminal section; belongs to the GTP cyclohydrolase II family. | Riboflavin synthase, alpha subunit. | 0.999 |
ribA | ribD | PNK_1224 | PNK_0848 | Putative 3,4-dihydroxy-2-butanone 4-phosphate synthase/GTP cyclohydrolase II; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the C-terminal section; belongs to the GTP cyclohydrolase II family. | Diaminohydroxyphosphoribosylaminopyrimidine deaminase; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | 0.999 |
ribA | ribF | PNK_1224 | PNK_1366 | Putative 3,4-dihydroxy-2-butanone 4-phosphate synthase/GTP cyclohydrolase II; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the C-terminal section; belongs to the GTP cyclohydrolase II family. | Putative riboflavin kinase/FMN adenylyltransferase; Belongs to the ribF family. | 0.580 |
ribA | ribH | PNK_1224 | PNK_1225 | Putative 3,4-dihydroxy-2-butanone 4-phosphate synthase/GTP cyclohydrolase II; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the C-terminal section; belongs to the GTP cyclohydrolase II family. | Riboflavin synthase, beta subunit; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin. | 0.999 |
ribC | ribA | PNK_1223 | PNK_1224 | Riboflavin synthase, alpha subunit. | Putative 3,4-dihydroxy-2-butanone 4-phosphate synthase/GTP cyclohydrolase II; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the C-terminal section; belongs to the GTP cyclohydrolase II family. | 0.999 |
ribC | ribD | PNK_1223 | PNK_0848 | Riboflavin synthase, alpha subunit. | Diaminohydroxyphosphoribosylaminopyrimidine deaminase; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | 0.999 |