STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
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[Homology]
Score
nadKATP-NAD/AcoX kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. (296 aa)    
Predicted Functional Partners:
nadD
Nicotinate (nicotinamide) nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).
  
 
 0.948
nadE
NAD+ synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source.
    
 0.946
cobB
PFAM: Silent information regulator protein Sir2; thiamine pyrophosphate protein central region; KEGG: pst:PSPTO_4675 transcriptional regulator, Sir2 family; Belongs to the sirtuin family. Class III subfamily.
  
 
 0.918
cobB-3
PFAM: Silent information regulator protein Sir2; KEGG: psp:PSPPH_4322 NAD-dependent deacetylase 4 (regulatory protein SIR2homolog 4); Belongs to the sirtuin family. Class III subfamily.
  
 
 0.918
ACA75547.1
KEGG: pen:PSEEN0115 pyridine proton-translocating NAD(P) transhydrogenase.
     
 0.918
ACA75546.1
NAD(P)(+) transhydrogenase (AB-specific); PFAM: alanine dehydrogenase/PNT domain protein; KEGG: pen:PSEEN0116 proton-translocating NAD(P) transhydrogenase.
     
 0.916
ACA75548.1
NAD(P)(+) transhydrogenase (AB-specific); The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane; Belongs to the PNT beta subunit family.
     
 0.908
sthA
Pyridine nucleotide-disulphide oxidoreductase dimerisation region; Conversion of NADPH, generated by peripheral catabolic pathways, to NADH, which can enter the respiratory chain for energy generation; Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
     
 0.907
nudC
PFAM: NUDIX hydrolase; NADH pyrophosphatase-like; Zinc ribbon NADH pyrophosphatase; KEGG: pen:PSEEN2184 NTP pyrophosphohydrolase.
     
 0.905
ACA71723.1
TIGRFAM: MazG family protein; PFAM: MazG nucleotide pyrophosphohydrolase; phosphoribosyl-ATP pyrophosphohydrolase; KEGG: pen:PSEEN1365 hypothetical protein.
     
 0.904
Your Current Organism:
Pseudomonas putida W619
NCBI taxonomy Id: 390235
Other names: P. putida W619, Pseudomonas putida str. W619, Pseudomonas putida strain W619
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