node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ACA72126.1 | surE | PputW619_1621 | PputW619_4055 | KEGG: pen:PSEEN3766 deoxyguanosinetriphosphate triphosphohydrolase (dGTPase) (dGTP triphosphohydrolase); TIGRFAM: deoxyguanosinetriphosphate triphosphohydrolase; SMART: metal-dependent phosphohydrolase HD region. | Stationary-phase survival protein SurE; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family. | 0.930 |
cmk | guaA | PputW619_1378 | PputW619_4193 | KEGG: pen:PSEEN1491 cytidylate kinase (cytidine monophosphate (CMP) kinase); TIGRFAM: cytidylate kinase; PFAM: cytidylate kinase region. | GMP synthase, large subunit; Catalyzes the synthesis of GMP from XMP. | 0.610 |
cmk | guaB | PputW619_1378 | PputW619_4194 | KEGG: pen:PSEEN1491 cytidylate kinase (cytidine monophosphate (CMP) kinase); TIGRFAM: cytidylate kinase; PFAM: cytidylate kinase region. | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.485 |
cmk | purH | PputW619_1378 | PputW619_4612 | KEGG: pen:PSEEN1491 cytidylate kinase (cytidine monophosphate (CMP) kinase); TIGRFAM: cytidylate kinase; PFAM: cytidylate kinase region. | KEGG: pen:PSEEN4863 phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase; TIGRFAM: phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase; PFAM: MGS domain protein; AICARFT/IMPCHase bienzyme formylation region. | 0.440 |
cmk | pyrF | PputW619_1378 | PputW619_1417 | KEGG: pen:PSEEN1491 cytidylate kinase (cytidine monophosphate (CMP) kinase); TIGRFAM: cytidylate kinase; PFAM: cytidylate kinase region. | Orotidine 5'-phosphate decarboxylase; Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP); Belongs to the OMP decarboxylase family. Type 1 subfamily. | 0.721 |
cmk | pyrH | PputW619_1378 | PputW619_4080 | KEGG: pen:PSEEN1491 cytidylate kinase (cytidine monophosphate (CMP) kinase); TIGRFAM: cytidylate kinase; PFAM: cytidylate kinase region. | Uridylate kinase; Catalyzes the reversible phosphorylation of UMP to UDP. | 0.688 |
cmk | pyrR | PputW619_1378 | PputW619_0467 | KEGG: pen:PSEEN1491 cytidylate kinase (cytidine monophosphate (CMP) kinase); TIGRFAM: cytidylate kinase; PFAM: cytidylate kinase region. | Uracil phosphoribosyltransferase; Regulates the transcription of the pyrimidine nucleotide (pyr) operon in response to exogenous pyrimidines. | 0.738 |
cmk | surE | PputW619_1378 | PputW619_4055 | KEGG: pen:PSEEN1491 cytidylate kinase (cytidine monophosphate (CMP) kinase); TIGRFAM: cytidylate kinase; PFAM: cytidylate kinase region. | Stationary-phase survival protein SurE; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family. | 0.931 |
guaA | cmk | PputW619_4193 | PputW619_1378 | GMP synthase, large subunit; Catalyzes the synthesis of GMP from XMP. | KEGG: pen:PSEEN1491 cytidylate kinase (cytidine monophosphate (CMP) kinase); TIGRFAM: cytidylate kinase; PFAM: cytidylate kinase region. | 0.610 |
guaA | guaB | PputW619_4193 | PputW619_4194 | GMP synthase, large subunit; Catalyzes the synthesis of GMP from XMP. | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.999 |
guaA | purH | PputW619_4193 | PputW619_4612 | GMP synthase, large subunit; Catalyzes the synthesis of GMP from XMP. | KEGG: pen:PSEEN4863 phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase; TIGRFAM: phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase; PFAM: MGS domain protein; AICARFT/IMPCHase bienzyme formylation region. | 0.910 |
guaA | pyrF | PputW619_4193 | PputW619_1417 | GMP synthase, large subunit; Catalyzes the synthesis of GMP from XMP. | Orotidine 5'-phosphate decarboxylase; Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP); Belongs to the OMP decarboxylase family. Type 1 subfamily. | 0.687 |
guaA | pyrH | PputW619_4193 | PputW619_4080 | GMP synthase, large subunit; Catalyzes the synthesis of GMP from XMP. | Uridylate kinase; Catalyzes the reversible phosphorylation of UMP to UDP. | 0.794 |
guaA | pyrR | PputW619_4193 | PputW619_0467 | GMP synthase, large subunit; Catalyzes the synthesis of GMP from XMP. | Uracil phosphoribosyltransferase; Regulates the transcription of the pyrimidine nucleotide (pyr) operon in response to exogenous pyrimidines. | 0.578 |
guaA | surE | PputW619_4193 | PputW619_4055 | GMP synthase, large subunit; Catalyzes the synthesis of GMP from XMP. | Stationary-phase survival protein SurE; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family. | 0.961 |
guaB | cmk | PputW619_4194 | PputW619_1378 | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | KEGG: pen:PSEEN1491 cytidylate kinase (cytidine monophosphate (CMP) kinase); TIGRFAM: cytidylate kinase; PFAM: cytidylate kinase region. | 0.485 |
guaB | guaA | PputW619_4194 | PputW619_4193 | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | GMP synthase, large subunit; Catalyzes the synthesis of GMP from XMP. | 0.999 |
guaB | purH | PputW619_4194 | PputW619_4612 | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | KEGG: pen:PSEEN4863 phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase; TIGRFAM: phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase; PFAM: MGS domain protein; AICARFT/IMPCHase bienzyme formylation region. | 0.974 |
guaB | pyrF | PputW619_4194 | PputW619_1417 | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | Orotidine 5'-phosphate decarboxylase; Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP); Belongs to the OMP decarboxylase family. Type 1 subfamily. | 0.520 |
guaB | pyrH | PputW619_4194 | PputW619_4080 | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | Uridylate kinase; Catalyzes the reversible phosphorylation of UMP to UDP. | 0.490 |