node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
SEQ94352.1 | SER38881.1 | SAMN04488023_102225 | SAMN04488023_10896 | Branched-chain amino acid aminotransferase. | 2-isopropylmalate synthase; Belongs to the alpha-IPM synthase/homocitrate synthase family. | 0.950 |
SEQ94352.1 | SER39074.1 | SAMN04488023_102225 | SAMN04488023_108104 | Branched-chain amino acid aminotransferase. | Acetolactate synthase, small subunit. | 0.541 |
SEQ94352.1 | SER39103.1 | SAMN04488023_102225 | SAMN04488023_108105 | Branched-chain amino acid aminotransferase. | Acetolactate synthase, large subunit. | 0.537 |
SEQ94352.1 | SER39200.1 | SAMN04488023_102225 | SAMN04488023_108109 | Branched-chain amino acid aminotransferase. | Branched-chain amino acid aminotransferase. | 0.903 |
SEQ94352.1 | ilvD | SAMN04488023_102225 | SAMN04488023_108107 | Branched-chain amino acid aminotransferase. | Dihydroxyacid dehydratase; Belongs to the IlvD/Edd family. | 0.967 |
SER13377.1 | SER38881.1 | SAMN04488023_104241 | SAMN04488023_10896 | Branched-chain amino acid aminotransferase. | 2-isopropylmalate synthase; Belongs to the alpha-IPM synthase/homocitrate synthase family. | 0.950 |
SER13377.1 | SER39074.1 | SAMN04488023_104241 | SAMN04488023_108104 | Branched-chain amino acid aminotransferase. | Acetolactate synthase, small subunit. | 0.541 |
SER13377.1 | SER39103.1 | SAMN04488023_104241 | SAMN04488023_108105 | Branched-chain amino acid aminotransferase. | Acetolactate synthase, large subunit. | 0.605 |
SER13377.1 | ilvD | SAMN04488023_104241 | SAMN04488023_108107 | Branched-chain amino acid aminotransferase. | Dihydroxyacid dehydratase; Belongs to the IlvD/Edd family. | 0.982 |
SER38881.1 | SEQ94352.1 | SAMN04488023_10896 | SAMN04488023_102225 | 2-isopropylmalate synthase; Belongs to the alpha-IPM synthase/homocitrate synthase family. | Branched-chain amino acid aminotransferase. | 0.950 |
SER38881.1 | SER13377.1 | SAMN04488023_10896 | SAMN04488023_104241 | 2-isopropylmalate synthase; Belongs to the alpha-IPM synthase/homocitrate synthase family. | Branched-chain amino acid aminotransferase. | 0.950 |
SER38881.1 | SER39074.1 | SAMN04488023_10896 | SAMN04488023_108104 | 2-isopropylmalate synthase; Belongs to the alpha-IPM synthase/homocitrate synthase family. | Acetolactate synthase, small subunit. | 0.980 |
SER38881.1 | SER39103.1 | SAMN04488023_10896 | SAMN04488023_108105 | 2-isopropylmalate synthase; Belongs to the alpha-IPM synthase/homocitrate synthase family. | Acetolactate synthase, large subunit. | 0.985 |
SER38881.1 | SER39200.1 | SAMN04488023_10896 | SAMN04488023_108109 | 2-isopropylmalate synthase; Belongs to the alpha-IPM synthase/homocitrate synthase family. | Branched-chain amino acid aminotransferase. | 0.970 |
SER38881.1 | ilvC | SAMN04488023_10896 | SAMN04488023_108103 | 2-isopropylmalate synthase; Belongs to the alpha-IPM synthase/homocitrate synthase family. | Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. | 0.907 |
SER38881.1 | ilvD | SAMN04488023_10896 | SAMN04488023_108107 | 2-isopropylmalate synthase; Belongs to the alpha-IPM synthase/homocitrate synthase family. | Dihydroxyacid dehydratase; Belongs to the IlvD/Edd family. | 0.996 |
SER38881.1 | leuB | SAMN04488023_10896 | SAMN04488023_10897 | 2-isopropylmalate synthase; Belongs to the alpha-IPM synthase/homocitrate synthase family. | 3-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate. | 0.992 |
SER38881.1 | leuC | SAMN04488023_10896 | SAMN04488023_108102 | 2-isopropylmalate synthase; Belongs to the alpha-IPM synthase/homocitrate synthase family. | 3-isopropylmalate dehydratase, large subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. | 0.998 |
SER38881.1 | leuD | SAMN04488023_10896 | SAMN04488023_10899 | 2-isopropylmalate synthase; Belongs to the alpha-IPM synthase/homocitrate synthase family. | 3-isopropylmalate dehydratase, small subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. Belongs to the LeuD family. LeuD type 1 subfamily. | 0.999 |
SER39074.1 | SEQ94352.1 | SAMN04488023_108104 | SAMN04488023_102225 | Acetolactate synthase, small subunit. | Branched-chain amino acid aminotransferase. | 0.541 |