node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
OKY52512.1 | hisA | BSR42_12490 | BSR42_01435 | Cobyric acid decarboxylase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino]imidazole-4- carboxamide isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.726 |
OKY52512.1 | hisB | BSR42_12490 | BSR42_01445 | Cobyric acid decarboxylase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Imidazoleglycerol-phosphate dehydratase; Catalyzes the dehydration of D-erythro-1-(imidazol-4-yl)glycerol 3-phosphate to 3-(imidazol-4-yl)-2-oxopropyl phosphate in histidine biosynthesis; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.945 |
OKY52512.1 | hisD | BSR42_12490 | BSR42_01455 | Cobyric acid decarboxylase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Histidinol dehydrogenase; Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine. | 0.926 |
OKY52512.1 | hisF | BSR42_12490 | BSR42_01430 | Cobyric acid decarboxylase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Imidazole glycerol phosphate synthase subunit HisF; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit. | 0.843 |
OKY52512.1 | hisG | BSR42_12490 | BSR42_01460 | Cobyric acid decarboxylase; Derived by automated computational analysis using gene prediction method: Protein Homology. | ATP phosphoribosyltransferase; Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity. Belongs to the ATP phosphoribosyltransferase family. Short subfamily. | 0.957 |
OKY52512.1 | hisH | BSR42_12490 | BSR42_01440 | Cobyric acid decarboxylase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Imidazole glycerol phosphate synthase subunit HisH; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF. | 0.837 |
OKY52512.1 | hisI | BSR42_12490 | BSR42_01425 | Cobyric acid decarboxylase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP diphosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology; In the N-terminal section; belongs to the PRA-CH family. | 0.968 |
OKY52512.1 | hisZ | BSR42_12490 | BSR42_01465 | Cobyric acid decarboxylase; Derived by automated computational analysis using gene prediction method: Protein Homology. | ATP phosphoribosyltransferase regulatory subunit; Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine. | 0.684 |
OKY54519.1 | hisA | BSR42_01450 | BSR42_01435 | Histidinol-phosphate transaminase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino]imidazole-4- carboxamide isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.977 |
OKY54519.1 | hisB | BSR42_01450 | BSR42_01445 | Histidinol-phosphate transaminase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Imidazoleglycerol-phosphate dehydratase; Catalyzes the dehydration of D-erythro-1-(imidazol-4-yl)glycerol 3-phosphate to 3-(imidazol-4-yl)-2-oxopropyl phosphate in histidine biosynthesis; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.999 |
OKY54519.1 | hisD | BSR42_01450 | BSR42_01455 | Histidinol-phosphate transaminase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Histidinol dehydrogenase; Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine. | 0.998 |
OKY54519.1 | hisF | BSR42_01450 | BSR42_01430 | Histidinol-phosphate transaminase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Imidazole glycerol phosphate synthase subunit HisF; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit. | 0.988 |
OKY54519.1 | hisG | BSR42_01450 | BSR42_01460 | Histidinol-phosphate transaminase; Derived by automated computational analysis using gene prediction method: Protein Homology. | ATP phosphoribosyltransferase; Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity. Belongs to the ATP phosphoribosyltransferase family. Short subfamily. | 0.994 |
OKY54519.1 | hisH | BSR42_01450 | BSR42_01440 | Histidinol-phosphate transaminase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Imidazole glycerol phosphate synthase subunit HisH; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF. | 0.988 |
OKY54519.1 | hisI | BSR42_01450 | BSR42_01425 | Histidinol-phosphate transaminase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP diphosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology; In the N-terminal section; belongs to the PRA-CH family. | 0.997 |
OKY54519.1 | hisZ | BSR42_01450 | BSR42_01465 | Histidinol-phosphate transaminase; Derived by automated computational analysis using gene prediction method: Protein Homology. | ATP phosphoribosyltransferase regulatory subunit; Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine. | 0.928 |
OKY54858.1 | hisA | BSR42_00720 | BSR42_01435 | Threonine-phosphate decarboxylase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino]imidazole-4- carboxamide isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.726 |
OKY54858.1 | hisB | BSR42_00720 | BSR42_01445 | Threonine-phosphate decarboxylase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Imidazoleglycerol-phosphate dehydratase; Catalyzes the dehydration of D-erythro-1-(imidazol-4-yl)glycerol 3-phosphate to 3-(imidazol-4-yl)-2-oxopropyl phosphate in histidine biosynthesis; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.960 |
OKY54858.1 | hisD | BSR42_00720 | BSR42_01455 | Threonine-phosphate decarboxylase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Histidinol dehydrogenase; Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine. | 0.964 |
OKY54858.1 | hisF | BSR42_00720 | BSR42_01430 | Threonine-phosphate decarboxylase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Imidazole glycerol phosphate synthase subunit HisF; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit. | 0.850 |