STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
phnXPhosphonoacetaldehyde hydrolase; Involved in phosphonate degradation; Belongs to the HAD-like hydrolase superfamily. PhnX family. (255 aa)    
Predicted Functional Partners:
phnW-2
2-aminoethylphosphonate--pyruvate transaminase; Involved in phosphonate degradation; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. PhnW subfamily.
  
  0.985
phnW
2-aminoethylphosphonate--pyruvate aminotransferase; Involved in phosphonate degradation; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. PhnW subfamily.
  
  0.951
OKY53361.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
  0.799
BSR42_07215
ABC transporter substrate-binding protein; Internal stop; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.792
OKY54161.1
Phosphate ABC transporter substrate-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.755
phnC
Phosphonate ABC transporter permease; Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. Phosphonates importer (TC 3.A.1.9.1) family.
 
     0.721
cinA
Competence/damage-inducible protein A; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the CinA family.
    
  0.629
guaB
IMP dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
    
  0.628
OKY53077.1
Chorismate mutase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
  0.578
OKY53476.1
ABC transporter; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.557
Your Current Organism:
Megasphaera cerevisiae
NCBI taxonomy Id: 39029
Other names: ATCC 43254, DSM 20462, JCM 6130, M. cerevisiae, VTT E-85230, strain PAT 1
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