Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Ldb0094L-2-hydroxyisocaproate dehydrogenase; Belongs to the LDH/MDH superfamily. (302 aa)    
Predicted Functional Partners:
pyk
Pyruvate kinase; Belongs to the pyruvate kinase family.
  
 0.982
Ldb1010
Conserved hypothetical protein (fragment); Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
  
 0.957
ldhA
D-lactate dehydrogenase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
  
 0.949
pox1
Pyruvate oxidase; Belongs to the TPP enzyme family.
  
 0.935
ldh
L-lactate dehydrogenase; Catalyzes the conversion of lactate to pyruvate.
  
  
0.925
pgi
Glucose-6-phosphate isomerase.
  
 0.913
gapN
Homoserine O-succinyltransferase (fragment); Belongs to the aldehyde dehydrogenase family.
  
 0.898
gpd
Glucose-6-phosphate 1-dehydrogenase; Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone.
   
 
 0.850
fba
Fructose-bisphosphate aldolase.
   
 
 0.849
ilvE
Branched-chain amino acid aminotransferase.
  
 0.848
Your Current Organism:
Lactobacillus delbrueckii
NCBI taxonomy Id: 390333
Other names: L. delbrueckii subsp. bulgaricus ATCC 11842 = JCM 1002, Lactobacillus delbrueckii subsp. bulgaricus ATCC 11842, Lactobacillus delbrueckii subsp. bulgaricus ATCC 11842 = JCM 1002, Lactobacillus delbrueckii subsp. bulgaricus DSM 20081
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