Nodes:
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
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[Homology]
Score
metEPutative methionine synthase. (374 aa)    
Predicted Functional Partners:
metK
S-adenosylmethionine synthetase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
  
 0.855
Ldb0313
6 Protein of unknown function, without similarity to other proteins.
  
  
 0.710
luxS
S-ribosylhomocysteinase (Autoinducer-2 production protein LuxS) (AI-2 synthesis protein); Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD). Belongs to the LuxS family.
    
 0.677
Ldb0115
Transcriptional regulator (LysR family); Belongs to the LysR transcriptional regulatory family.
  
  
 0.571
fhs
Formate-tetrahydrofolate ligase; Belongs to the formate--tetrahydrofolate ligase family.
  
 
 0.561
Ldb1326
Conserved hypothetical protein; Putative Cystathionine beta-lyase or Cystathionine gamma-synthase.
  
  
 0.539
Ldb1707
Acetaldehyde dehydrogenase.
     
 0.457
guaA
GMP synthase; Catalyzes the synthesis of GMP from XMP.
   
  
 0.433
Ldb1350
Homoserine dehydrogenase.
  
  
 0.428
ask
Aspartate kinase; Belongs to the aspartokinase family.
  
  
 0.420
Your Current Organism:
Lactobacillus delbrueckii
NCBI taxonomy Id: 390333
Other names: L. delbrueckii subsp. bulgaricus ATCC 11842 = JCM 1002, Lactobacillus delbrueckii subsp. bulgaricus ATCC 11842, Lactobacillus delbrueckii subsp. bulgaricus ATCC 11842 = JCM 1002, Lactobacillus delbrueckii subsp. bulgaricus DSM 20081
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