Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
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Co-occurrence
Co-expression
Experiments
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[Homology]
Score
Ldb0314Putative transcriptional regulator (MarR family). (149 aa)    
Predicted Functional Partners:
Ldb1180
Glycine betaine ABC transporter, substrate binding / permease protein.
  
  
 0.780
Ldb0313
6 Protein of unknown function, without similarity to other proteins.
  
  
 0.763
ansA
Asparaginase.
       0.746
scrB
Sucrose-6-phosphate hydrolase (fragment).
   
  
 0.547
Ldb1285
6 Protein of unknown function, without similarity to other proteins.
  
  
 0.497
Ldb2038
ABC transporter, ATP-binding protein.
  
  
 0.497
Ldb0667
6 Protein of unknown function, without similarity to other proteins.
 
  
 0.495
Ldb0486
6 Protein of unknown function, without similarity to other proteins.
  
  
 0.423
topA
DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]
     
 0.423
Ldb2142
ABC transporter, ATP-binding/permease protein.
 
   
 0.411
Your Current Organism:
Lactobacillus delbrueckii
NCBI taxonomy Id: 390333
Other names: L. delbrueckii subsp. bulgaricus ATCC 11842 = JCM 1002, Lactobacillus delbrueckii subsp. bulgaricus ATCC 11842, Lactobacillus delbrueckii subsp. bulgaricus ATCC 11842 = JCM 1002, Lactobacillus delbrueckii subsp. bulgaricus DSM 20081
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